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- Table of Contents
Mannose-binding protein C Antibodies
AND MBL2 ELISA kits, Mannose-binding protein C Proteins
Many biological assays use antibodies to detect Mannose-binding protein C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mannose-binding protein C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mannose-binding protein C antibodies...
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MBL2 Infographic by Boster Bio
All MBL2 Products
Product
Figures
Specificity
Applications
Price
Human MBL2/MPB-C ELISA Kit PicoKine®
3 Citations 9 Q&As
Human
ELISA
$499
Cat # EK0805
96 wells/kit, with removable strips.
Cat # EK0805
96 wells/kit, with removable strips.
Mouse MBL2/MPB-C ELISA Kit PicoKine®
1 Citations 4 Q&As
Mouse
ELISA
$499
Cat # EK0806
96 wells/kit, with removable strips.
Cat # EK0806
96 wells/kit, with removable strips.
Mouse
ELISA
$500
Cat # EZ0806
For 5 plates, 96 wells each
Cat # EZ0806
For 5 plates, 96 wells each
Human MBL2/MPB-C PicoKine® Quick ELISA Kit
1 Citations
Human
ELISA
$499
Cat # FEK0805
96 wells/kit, with removable strips.
Cat # FEK0805
96 wells/kit, with removable strips.
Human
IF, IHC, WB
$523
Cat # M01000
100 µl
Cat # M01000
100 µl
MBL2 Overview
Facts about Mannose-binding protein C.
Mannose-binding protein C (MBL2)
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway.
Binds to late apoptotic cells, and to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Gene Information
| Human | |
|---|---|
| Gene Name: | MBL2 |
| Uniprot: | P11226 |
| Entrez: | 4153 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
COLEC1; COLEC1collectin-1; Collectin-1; HSMBPC; Mannan-binding protein; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin (protein C) 2, soluble; Mannose-binding lectin; mannose-binding protein C; MBL; MBL2; MBL2D; MBLmannan-binding lectin; MBP; MBP1; MBP1mannose-binding lectin 2, soluble (opsonic defect); MBP-C; MGC116832; MGC116833
Molecular Weight
Mass (kDA):
26.144 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q21.1 |
| Sequence: | 10; NC_000010.11 (52765380..52772784, complement) |
Tissue Specificity
Plasma protein produced mainly in the liver.
Subcellular Localizations
Secreted.
Diseases
- Infective Disorder
- Inflammation
- Autoimmune Reaction
- Autoimmune Diseases
- Systemic Infection
- Pneumonia
- Hiv Infections
- Fibrosis
- Respiratory Tract Infections
- Innate Immune Response
- Malignant Neoplasms
- Cystic Fibrosis
- Virus Diseases
Interacting Proteins
- LRP1
Pathways
- Complement Activation
- Pathogenesis
- Immune Response
- Innate Immune Response
- Phagocytosis
- Inflammatory Response
- Localization
- Opsonization
- Sensitization
- Acute-phase Response
- Dna Repair
- Adaptive Immune Response
- Reverse Transcription
PTMs
- Glycosylation
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MBL2
bosterbio.com/bosterbio-gene-info-cards/MBL2
References
PMID: 2450948 by Ezekowitz R.A.B., et al. A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectins.
PMID: 2477486 by Sastry K., et al. The human mannose-binding protein gene. Exon structure reveals its evolutionary relationship to a human pulmonary surfactant gene and localization to chromosome 10.
1 Publications of Boster Mannose-binding protein C Antibodies & ELISA Kits
- PubMed ID: 29653582, Gomaa MH, Ali SS, Fattouh AM, Hamza HS, Badr MM. Pediatr Rheumatol Online J. 201...
*More publications can be found for each product on its corresponding product page