MC1R Antibodies

AND MC1R ELISA kits, MC1R Proteins

Many biological assays use antibodies to detect MC1R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MC1R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MC1R antibodies...

We validate the specificity of these antibodies to MC1R by testing them on tissues known to express MC1R positively and negatively. Browse below to find the MC1R antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for MC1R? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MC1R Western Blot Guide

MC1R Infographic by Boster Bio

All MC1R Products

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Product

Figures

Specificity

Applications

Price

Anti-MC1 Receptor/MC1R Antibody Picoband®

1 Citations

Western blot analysis of MC1 using anti-MC1 antibody (A00855-1)

Human, Mouse, Rat

$370
Cat # A00855-1
100 μg/vial

Anti-MC1 Receptor Rabbit Monoclonal Antibody

Western blot analysis of MC1 Receptor expression in A375 cell lysate

Human

IHC, WB

$370
Cat # M00855
100 μl/vial

Anti-MSHR MC1R Antibody

Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma

Western Blot analysis of COLO205 cells using MC1-R Polyclonal Antibody

Western blot analysis of the lysates from HepG2 cells using MSHR antibody

Human, Mouse, Rat

ELISA, IHC, WB

$335
Cat # A30842
100ul

MC1 Receptor (MC1R) (NM_002386) Human Over-expression Lysate

Human

$628
Cat # LS004157
20 µg, 100 µg

MC1R Overview

Facts about Melanocyte-stimulating hormone receptor.

MC1R 3D structure. Source: alphafold

Melanocyte-stimulating hormone receptor (MC1R)

Receptor for MSH (alpha, beta and gamma) and ACTH.
The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

Gene Information

Human
Gene Name:	MC1R
Uniprot:	Q01726
Entrez:	4157

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

CMM5; MC1R; MC1-R; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); Melanocortin receptor 1; Melanocortin-1 R; Melanocortin1R; Melanocortin-1R; melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; MSH-R; Mshra; MSH-RMGC14337; SHEP2; Tob

Molecular Weight

Mass (kDA):
34.706 kDA

Genomic Context


Human

Location:	16q24.3
Sequence:	16; NC_000016.10 (89918862..89920972)

Tissue Specificity

Melanocytes and corticoadrenal tissue.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Melanoma
Skin Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Skin
Neoplasms
Malignant Paraganglionic Neoplasm
Cutaneous Melanoma
Melanocytic Nevus
Obesity
Melanosis
Albinism
Inflammation
Carcinoma

Sunburn
Basal Cell Carcinoma
Neoplasm Metastasis
Melanoma, Experimental
Hereditary Melanoma
Skin Carcinoma
Albinism, Oculocutaneous

Interacting Proteins

MRAP

Pathways

Pigmentation
Energy Homeostasis
Dna Repair
Pathogenesis
Localization
Cell Cycle
Photoprotection
Inflammatory Response
Translation
Feeding Behavior
Response To Uv
Cell Proliferation
Immune Response

Transport
Melanocyte Proliferation
Cell Growth
Cell Migration
Reverse Transcription
Paracrine Signaling
Mating

PTMs

Phosphorylation
Acetylation
Cleavage
Glycosylation

Amidation
Oxidation
Acylation
Ubiquitination

Iodination

Research Areas

GPCR
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MC1R

References

PMID: 1325670 by Mountjoy K.G., et al. The cloning of a family of genes that encode the melanocortin receptors.

PMID: 8463333 by Gantz I., et al. Molecular cloning of a novel melanocortin receptor.