MGAT4C Antibodies

AND MGAT4C ELISA kits, MGAT4C Proteins

Many biological assays use antibodies to detect MGAT4C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MGAT4C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MGAT4C antibodies...

We validate the specificity of these antibodies to MGAT4C by testing them on tissues known to express MGAT4C positively and negatively. Browse below to find the MGAT4C antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MGAT4C Infographic by Boster Bio

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MGAT4C Overview

Facts about Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C.

MGAT4C 3D structure. Source: alphafold

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C)

Glycosyltransferase that engages in the transfer of N-acetylglucosamine (GlcNAc) into the center mannose residues of N- linked glycans. Catalyzes the formation of this GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans.

Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc into the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity).

Gene Information

Human
Gene Name:	MGAT4C
Uniprot:	Q9UBM8
Entrez:	25834

Family

Belongs to:

glycosyltransferase 54 family

Alternative Names

GNTIVH; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative); UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV

Molecular Weight

Mass (kDA):
56.061 kDA

Genomic Context


Human

Location:	12q21.31-q21.32
Sequence:	12; NC_000012.12 (85955667..86839000, complement)

Tissue Specificity

Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms

Pathways

N-glycan Processing
Cell Proliferation
Rna Interference

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MGAT4C

References

PMID: 10570912 by Furukawa T., et al. Cloning and characterization of the human UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV- homologue (hGnT-IV-H) gene.

PMID: 10962001 by Sakamoto Y., et al. Molecular cloning and expression of cDNA encoding chicken UDP-N- acetyl-D-glucosamine (GlcNAc): GlcNAcbeta 1-6(GlcNAcbeta 1-2)-manalpha 1-R[GlcNAc to man]beta 1,4N-acetylglucosaminyltransferase VI.