Mgrn1 Antibodies

AND Mgrn1 ELISA kits, Mgrn1 Proteins

Many biological assays use antibodies to detect Mgrn1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mgrn1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mgrn1 antibodies...

We validate the specificity of these antibodies to Mgrn1 by testing them on tissues known to express Mgrn1 positively and negatively. Browse below to find the Mgrn1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Mgrn1 Infographic by Boster Bio

All Mgrn1 Products

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Product

Figures

Specificity

Applications

Price

Anti-MGRN1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05951
100ul

Anti-RNF156 (MGRN1) Mouse Monoclonal Antibody [Clone ID: OTI3C3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MGRN1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MGRN1 monoclonal antibody

HEK293T cells transfected with either MGRN1 (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-MGRN1 antibody (M05951)

Human, Monkey, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M05951
100 µl

RNF156 (MGRN1) (NM_015246) Human Over-expression Lysate

RNF156 (MGRN1) Human Over-expression Lysates NM_001142290

Human

$628
Cat # LS023295
20 µg, 100 µg

Anti-RNF156/MGRN1 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A05951-1
100 μl/vial

Mgrn1 Overview

Facts about E3 ubiquitin-protein ligase MGRN1.

E3 ubiquitin-protein ligase MGRN1 (Mgrn1)

Mediates TSG101 monoubiquitination at multiple sites. Plays a role in the regulation of endosome-to-lysosome trafficking.

Impairs MC1R- and MC4R-signaling by competing GNAS-binding into MCRs and inhibiting agonist-induced cAMP production. Does not inhibit ADRB2-signaling.

Gene Information

Mouse
Gene Name:	Mgrn1
Uniprot:	Q9D074
Entrez:	17237

Family

Belongs to:

No superfamily

Alternative Names

E3 ubiquitin-protein ligase MGRN1; EC 6.3.2; KIAA0544probable E3 ubiquitin-protein ligase MGRN1; Mahogunin RING finger protein 1; mahogunin, ring finger 1; RING finger protein 156; RNF156EC 6.3.2.-

Molecular Weight

Mass (kDA):
58.477 kDA

Genomic Context


Mouse

Location:	16 A1\|16 2.48 cM
Sequence:	16;

Tissue Specificity

Widely expressed, with highest levels in brain, heart, kidney and liver. In the CNS, especially prominent in the Purkinje cells of the cerebellum. In the skin, expressed in the basal layer of the epidermis and hair follicles, primarily in the outer root sheath. Isoforms 1, 3, 4 and 5 are equally expressed in the liver. Isoforms 1, 3 and 4 are most abundant in brain, kidney and heart, respectively.