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- Table of Contents
Facts about Major intrinsically disordered Notch2-binding receptor 1.
Negatively regulates cell growth (PubMed:29329397, PubMed:30080879). Negatively regulates neurite outgrowth in hippocampal neurons (By similarity).
| Human | |
|---|---|
| Gene Name: | MINAR1 |
| Uniprot: | Q9UPX6 |
| Entrez: | 23251 |

| Belongs to: |
|---|
| MINAR family |

Major intrinsically disordered Notch2-binding receptor 1
Mass (kDA):
102.993 kDA

| Human | |
|---|---|
| Location: | 15q25.1 |
| Sequence: | 15; NC_000015.10 (79411557..79472304) |
Widely expressed, including in breast epithelial cells and endothelial cells (at protein level). Expression is down-regulated in advanced breast tumors (at protein level).
Cell membrane; Single-pass type IV membrane protein.


PMID: 29329397 by Ho R.X., et al. MINAR1 is a Notch2-binding protein that inhibits angiogenesis and breast cancer growth.
PMID: 30080879 by Zhang H., et al. UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling.