MLH3 Antibodies

AND MLH3 ELISA kits, MLH3 Proteins

Many biological assays use antibodies to detect MLH3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MLH3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MLH3 antibodies...

We validate the specificity of these antibodies to MLH3 by testing them on tissues known to express MLH3 positively and negatively. Browse below to find the MLH3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MLH3 Infographic by Boster Bio

All MLH3 Products

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Product

Figures

Specificity

Applications

Price

Anti-MLH3 Antibody

Western blot analysis of lysates from K562 and HT-29 cells, using MLH3 Antibody

Human

ELISA, IF, IHC, WB

$380
Cat # A04640
100ul

MLH3 (NM_014381) Human Over-expression Lysate

Human

$960
Cat # LS027030
20 µg, 100 µg

MLH3 Overview

Facts about DNA mismatch repair protein Mlh3.

MLH3 3D structure. Source: alphafold

DNA mismatch repair protein Mlh3 (MLH3)

Probably involved in the repair of mismatches in DNA. .

Gene Information

Human
Gene Name:	MLH3
Uniprot:	Q9UHC1
Entrez:	27030

Family

Belongs to:

DNA mismatch repair MutL/HexB family

Alternative Names

DNA mismatch repair protein Mlh3; HNPCC7; MGC138372; mutL (E. coli) homolog 3; mutL homolog 3 (E. coli); MutL protein homolog 3

Molecular Weight

Mass (kDA):
163.711 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (75013764..75051479, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Colorectal Cancer
Neoplasms
Hereditary Nonpolyposis Colorectal Cancer
Microsatellite Instability
Colorectal Neoplasms
Malignant Tumor Of Colon
Infertility
Cell Transformation, Neoplastic
Male Infertility
Carcinoma
Azoospermia

Carcinogenesis
Mutation, Out-of-frame
Sterility
Colonic Neoplasms
Endometrial Polyp
High-frequency Microsatellite Instability
Endometrial Carcinoma

Pathways

Mismatch Repair
Meiosis
Dna Repair
Prophase
Localization
Methylation
Metaphase
Spermatogenesis
Meiotic Prophase I
Dna Replication
Pachytene
Strand Invasion
Meiosis I

Cell Proliferation
Pathogenesis
Cell Migration
Fertilization
Dna Recombination
Regulation Of Gene Expression
Gene Conversion

PTMs

Methylation

Deamination

Research Areas

DNA Repair
Mismatch Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MLH3

References

PMID: 10615123 by Lipkin S.M., et al. MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability.

PMID: 11292842 by Kondo E., et al. The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2.