MMP15 Antibodies

AND MMP15 ELISA kits, MMP15 Proteins

Many biological assays use antibodies to detect MMP15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MMP15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MMP15 antibodies...

We validate the specificity of these antibodies to MMP15 by testing them on tissues known to express MMP15 positively and negatively. Browse below to find the MMP15 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MMP15 Infographic by Boster Bio

All MMP15 Products

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Applications

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MMP-15 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from MDA-MB-435 cells

Human, Mouse

ELISA

$480
Cat # EKC1377
1 kit, containing one 96-well plate and all necessary reagents

Anti-Cleaved-MMP-15 (Y132) Antibody

Western blot (WB) analysis of Cleaved-MMP-15 (Y132) pAb at 1:500 dilution
Lane1:MCF-7 whole cell lysate(40ug)
Lane2:SGC7901 whole cell lysate(40ug)
Lane3:HCT116 whole cell lysate(40ug)
Lane4:HEK293T whole cell lysate(40ug)

Human

$405
Cat # A06396Y132
100ul

Anti-MT2-MMP/MMP15 Antibody Picoband®

Western blot analysis of MT2-MMP/MMP15 using anti-MT2-MMP/MMP15 antibody (A06396-1)

IF analysis of MT2-MMP/MMP15 using anti-MT2-MMP/MMP15 antibody (A06396-1)

Flow Cytometry analysis of CACO-2 cells using anti-MT2-MMP/MMP15 antibody (A06396-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A06396-1
100 μg/vial

MMP15 (NM_002428) Human Over-expression Lysate

Human

$628
Cat # LS004324
20 µg, 100 µg

MMP15 Overview

Facts about Matrix metalloproteinase-15.

MMP15 3D structure. Source: alphafold

Matrix metalloproteinase-15 (MMP15)

Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.

Gene Information

Human
Gene Name:	MMP15
Uniprot:	P51511
Entrez:	4324

Family

Belongs to:

peptidase M10A family

Alternative Names

EC 3.4.24; EC 3.4.24.-; EC 3.4.24.80; matrix metallopeptidase 15 (membrane-inserted); matrix metalloproteinase 15 (membrane-inserted); Membrane-type matrix metalloproteinase 2; Membrane-type-2 matrix metalloproteinase; MMP15; MMP-15; MT2-MMP; MT2-MMPMT2MMP; MTMMP2MT-MMP 2; SMCP-2matrix metalloproteinase-15

Molecular Weight

Mass (kDA):
75.807 kDA

Genomic Context


Human

Location:	16q21
Sequence:	16; NC_000016.10 (58025754..58046901)

Tissue Specificity

Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.

Subcellular Localizations

Membrane; Single-pass type I membrane protein; Extracellular side.

Diseases

Neoplasms
Cell Invasion
Neoplasm Metastasis
Carcinoma
Malignant Neoplasms
Neoplasm Invasiveness
Malignant Paraganglionic Neoplasm
Mammary Neoplasms
Cell Transformation, Neoplastic
Adenocarcinoma
Tumor Progression
Glioma

Malignant Squamous Cell Neoplasm
Metastatic Malignant Neoplasm To The Lymph Node
Tumor Angiogenesis
Tissue Adhesions
Malignant Neoplasm Of Breast
Inflammation
Carcinogenesis

Interacting Proteins

PROC

Pathways

Localization
Angiogenesis
Cell Adhesion
Proteolysis
Pathogenesis
Rna Interference
Transport
Cell Proliferation
Cell Migration
Gland Development
Tube Formation
Dna Methylation
Metaphase

Mammary Gland Development
Vasculogenesis
Syncytium Formation
Mesenchymal Cell Migration
Methylation
Menstruation
Reverse Transcription

PTMs

Cleavage

Methylation

Research Areas

Extracellular Matrix

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MMP15

References

PMID: 7649159 by Will H., et al. cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment.

PMID: 9119382 by Sato H., et al. Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization.