MPP2 Antibodies

AND MPP2 ELISA kits, MPP2 Proteins

Many biological assays use antibodies to detect MPP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MPP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MPP2 antibodies...

We validate the specificity of these antibodies to MPP2 by testing them on tissues known to express MPP2 positively and negatively. Browse below to find the MPP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for MPP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MPP2 Western Blot Guide

MPP2 Infographic by Boster Bio

All MPP2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-FOXM1 Antibody Picoband®

Western blot analysis of FOXM1 using anti-FOXM1 antibody (PB9194)

Human

$370
Cat # PB9194
100 μg/vial

Anti-MPP2 Antibody Picoband®

Western blot analysis of MPP2 using anti-MPP2 antibody (PB10079)

Human, Mouse, Rat

$370
Cat # PB10079
100 μg/vial

MPP2 (NM_005374) Human Over-expression Lysate

Human

$628
Cat # LS004355
20 µg, 100 µg

MPP2 Overview

Facts about MAGUK p55 subfamily member 2.

MPP2 3D structure. Source: alphafold

MAGUK p55 subfamily member 2 (MPP2)

Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules into core elements of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression (By similarity).

Appears to negatively regulate SRC function in epithelial cells (PubMed:19665017). .

Gene Information

Human
Gene Name:	MPP2
Uniprot:	Q14168
Entrez:	4355

Family

Belongs to:

MAGUK family

Alternative Names

Discs large homolog 2; DKFZp686A06252; DKFZp686J2189; DKFZp761D0712; DLG2discs large, homolog 2; MAGUK p55 subfamily member 2; membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2); Protein MPP2

Molecular Weight

Mass (kDA):
64.581 kDA

Genomic Context


Human

Location:	17q21.31
Sequence:	17; NC_000017.11 (43875357..43909711, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton. Membrane. Cell projection, dendrite. Cell junction, synapse, postsynaptic density. Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts.

Diseases

Neoplasms
Malignant Neoplasms
Nervousness
Tissue Adhesions
Cell Invasion
Lung Neoplasms
Malignant Neoplasm Of Lung
Chimera Disorder
Adenocarcinoma
Hypertrophy
Respiratory Failure
Adenocarcinoma Of Lung (disorder)
Schizophrenia

Retinoblastoma
Adenoma
Inflammation
Cell Transformation, Neoplastic
Cholangiocarcinoma
Peripheral Nerve Injuries
Muscular Dystrophy, Duchenne

Interacting Proteins

LIN7A

Pathways

Localization
Cell Cycle
Mitosis
Synaptic Transmission
Dna Replication
Cell Adhesion
Cell Proliferation
Proteolysis
Liver Development
Regeneration
Pathogenesis
Rna Interference
Transport

Cell Migration
Lung Development
M Phase
Vasculogenesis
Regulation Of Dendritic Spine Morphogenesis
Cytokinesis
Cell Differentiation

PTMs

Phosphorylation
Palmitoylation

Cleavage
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MPP2

References

PMID: 7590743 by Mazoyer S., et al. A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dlg-A.

PMID: 19665017 by Baumgartner M., et al. The PDZ protein MPP2 interacts with c-Src in epithelial cells.