MS4A3 Antibodies

AND MS4A3 ELISA kits, MS4A3 Proteins

Many biological assays use antibodies to detect MS4A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MS4A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MS4A3 antibodies...

We validate the specificity of these antibodies to MS4A3 by testing them on tissues known to express MS4A3 positively and negatively. Browse below to find the MS4A3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MS4A3 Infographic by Boster Bio

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MS4A3 (NM_006138) Human Over-expression Lysate

Human

$628
Cat # LS000932
20 µg, 100 µg

MS4A3 Overview

Facts about Membrane-spanning 4-domains subfamily A member 3.

MS4A3 3D structure. Source: alphafold

Membrane-spanning 4-domains subfamily A member 3 (MS4A3)

Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP).

Gene Information

Human
Gene Name:	MS4A3
Uniprot:	Q96HJ5
Entrez:	932

Family

Belongs to:

MS4A family

Alternative Names

CD20 antigen homolog; CD20 antigen-like protein; CD20L; CD20LIgE receptor beta subunit; hematopoietic cell 4 transmembrane protein; Hematopoietic-specific transmembrane protein 4; HTM4; HTM4IgE receptor beta chain; membrane-spanning 4-domains subfamily A member 3; membrane-spanning 4-domains, subfamily A, member 3 (hematopoieticcell-specific); MS4A3

Molecular Weight

Mass (kDA):
22.933 kDA

Genomic Context


Human

Location:	11q12.1
Sequence:	11; NC_000011.10 (60056628..60071116)

Tissue Specificity

Expressed specifically in hematopoietic cells and tissues.

Subcellular Localizations

Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Located in the perinuclear area.

Diseases

Myeloid Leukemia
Leukemia
Neurodegenerative Disorders
Anemia, Pernicious
Myeloid Leukemia, Chronic
Stomatitis
Leukemia, Myelocytic, Acute
Acute Erythroblastic Leukemia
Cardiovascular Diseases
Multiple Myeloma
Malignant Neoplasms
Neoplasms
Polycythemia

Lymphoma
Adenocarcinoma
Anemia
Hepatitis
Hypopigmentation Disorder
Severe Acute Respiratory Syndrome
Malignant Paraganglionic Neoplasm

Pathways

Cell Cycle
Pathogenesis
Transport
Drug Resistance
Cell Motility
Extracellular Matrix Organization
Oxygen Transport

Cell Cycle Arrest

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MS4A3

References

PMID: 7524084 by Adra C.N., et al. Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions.

PMID: 11781350 by Donato J.-L., et al. Human HTm4 is a hematopoietic cell cycle regulator.