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Msrb1 Antibodies
AND Msrb1 ELISA kits, Msrb1 Proteins
Many biological assays use antibodies to detect Msrb1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Msrb1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Msrb1 antibodies...
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Msrb1 Infographic by Boster Bio
All Msrb1 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS051734
20 µg, 100 µg
Cat # LS051734
20 µg, 100 µg
Msrb1 Overview
Facts about Methionine-R-sulfoxide reductase B1.
Methionine-R-sulfoxide reductase B1 (Msrb1)
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation after oxidative stress, methionine oxidation is also a post- translational modification that takes place on specific residue.
Acts as a regulator of actin assembly by reducing methionine (R)- sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Msrb1 |
| Uniprot: | Q9JLC3 |
| Entrez: | 27361 |
Family
| Belongs to: |
|---|
| MsrB Met sulfoxide reductase family |
Alternative Names
EC 1.8.4.-; methionine sulfoxide reductase; methionine-R-sulfoxide reductase B1; MGC3344; MsrB1; MSRB1selenoprotein R; Selenoprotein X; selenoprotein X, 1; SELR; SELX
Molecular Weight
Mass (kDA):
12.788 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 17 A3.3|17 12.53 cM |
| Sequence: | 17; |
Diseases
- Malignant Neoplasms
- Cataract
- Malignant Neoplasm Of Heart
- Intestinal Schistosomiasis
- Malignant Neoplasm Of Breast
- Communicable Diseases
- Endoplasmic Reticulum Stress
- Carcinoma
- Carcinogenesis
- Nervousness
- Senile Cataract
- Zinc Deficiency Disorder
Pathways
- Aging
- Regeneration
- Translation
- Protein Repair
- Transport
- Gene Silencing
- Photosynthesis
- Protein Oxidation
- Regulation Of Gene Expression
- Localization
- Intestinal Absorption
PTMs
- Reduction
- Oxidation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Msrb1
bosterbio.com/bosterbio-gene-info-cards/Msrb1
References
PMID: 10567350 by Kryukov G.V., et al. New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements.
PMID: 11929995 by Kryukov G.V., et al. Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase.