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- Table of Contents
Facts about Methionine-R-sulfoxide reductase B2, mitochondrial.
Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. .
| Human | |
|---|---|
| Gene Name: | MSRB2 |
| Uniprot: | Q9Y3D2 |
| Entrez: | 22921 |

| Belongs to: |
|---|
| MsrB Met sulfoxide reductase family |

CBS1; CBS-1methionine-r-sulfoxide reductase B2 variant 3; CGI-131; EC 1.8.4; EC 1.8.4.-; EC 1.8.4.12; methionine sulfoxide reductase B; methionine sulfoxide reductase B2; methionine-r-sulfoxide reductase B2 variant 1; methionine-R-sulfoxide reductase B2, mitochondrial; MGC26104; MSRB; MsrB2; PILB; pilin-like transcription factor
Mass (kDA):
19.536 kDA

| Human | |
|---|---|
| Location: | 10p12.2 |
| Sequence: | 10; NC_000010.11 (23095564..23122013) |
Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate.
Mitochondrion.





PMID: 10375640 by Huang W., et al. Identification, expression and chromosome localization of a human gene encoding a novel protein with similarity to the pilB family of transcriptional factors (pilin) and to bacterial peptide methionine sulfoxide reductases.
PMID: 15914630 by Marchetti M.A., et al. Methionine sulfoxide reductases B1, B2, and B3 are present in the human lens and confer oxidative stress resistance to lens cells.