Metallothionein-1A Antibodies

AND MT1A ELISA kits, Metallothionein-1A Proteins

Many biological assays use antibodies to detect Metallothionein-1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Metallothionein-1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Metallothionein-1A antibodies...

We validate the specificity of these antibodies to Metallothionein-1A by testing them on tissues known to express MT1A positively and negatively. Browse below to find the MT1A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MT1A Infographic by Boster Bio

All MT1A Products

Product

Figures

Specificity

Applications

Price

Anti-Metallothionein Antibody

Human, Rabbit

ELISA, WB

$553
Cat # M05542
100 ul

Metallothionein (MT1A) (NM_005946) Human Over-expression Lysate

Human

$628
Cat # LS004489
100 µg

MT1A Overview

Facts about Metallothionein-1A.

MT1A 3D structure. Source: alphafold

Metallothionein-1A (MT1A)

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. .

Gene Information

Human
Gene Name:	MT1A
Uniprot:	P04731
Entrez:	4489

Family

Belongs to:

metallothionein superfamily

Alternative Names

metallothionein 1A (functional); metallothionein 1A; metallothionein 1S; metallothionein-1A; metallothionein-IA; MGC32848; MT1; MT-1A; MT1S; MTC; MT-IA

Molecular Weight

Mass (kDA):
6.12 kDA

Genomic Context


Human

Location:	16q13
Sequence:	16; NC_000016.10 (56638666..56640087)

Diseases

Neoplasms
Malignant Neoplasms
Liver Carcinoma
Diabetes Mellitus
Liver Neoplasms
Inflammation
Carcinogenesis
Carcinoma
Diabetes Mellitus, Non-insulin-dependent
Cholangiocarcinoma
Malignant Neoplasm Of Urinary Bladder
Hepatitis

Malignant Paraganglionic Neoplasm
Prostatic Neoplasms
Cardiovascular Diseases
Arthropathy
Zinc Deficiency Disorder
Malignant Neoplasm Of Prostate
Malignant Neoplasm Of Breast

Interacting Proteins

GPR50
TP53

Pathways

Transport
Immune Response
Methylation
Cell Death
Secretion
Cell Cycle
Dna Methylation
Localization
Demethylation
Cell Growth
Excretion
Progesterone Secretion
Gene Silencing

Cellular Homeostasis
Nuclear Transport
Cell Division
Reverse Transcription
Fermentation
Drug Transport
Innate Immune Response

PTMs

Methylation
Demethylation

Reduction
Glycosylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MT1A

References

PMID: 6327055 by Richards R.I., et al. Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids.