MTNR1A Antibodies

AND MTNR1A ELISA kits, MTNR1A Proteins

Many biological assays use antibodies to detect MTNR1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTNR1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTNR1A antibodies...

We validate the specificity of these antibodies to MTNR1A by testing them on tissues known to express MTNR1A positively and negatively. Browse below to find the MTNR1A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTNR1A Infographic by Boster Bio

All MTNR1A Products

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Specificity

Applications

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Anti-MTR1A Antibody

2 Citations 5 Q&As

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung

Immunofluorescence analysis of HepG2 cells, using MTR1A Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$335
Cat # A30843
100ul

Anti-Melatonin receptor type 1A MTNR1A Antibody

Western blot (WB) analysis of MTNR1A polyclonal antibody at 1:500 dilution
Lane1:A549 whole cell lysate
Lane2:sp2/0 whole cell lysate
Lane3:PC12 whole cell lysate

Human, Mouse, Rat

$405
Cat # A06050
100ul

Melatonin Receptor 1A (MTNR1A) (NM_005958) Human Recombinant Protein

Coomassie blue staining of purified MTNR1A protein

$1062
Cat # PROTP48039
20 µg

Melatonin Receptor 1A (MTNR1A) (NM_005958) Human Over-expression Lysate

Human

$628
Cat # LS004543
20 µg, 100 µg

MTNR1A Overview

Facts about Melatonin receptor type 1A.

MTNR1A 3D structure. Source: alphafold

Melatonin receptor type 1A (MTNR1A)

High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin.

The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. .

Gene Information

Human
Gene Name:	MTNR1A
Uniprot:	P48039
Entrez:	4543

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

Mel1a receptor; Mel-1A-R; Melatonin R1A; melatonin receptor 1A; melatonin receptor type 1A; MelatoninR1A; MT1; MTNR1A

Molecular Weight

Mass (kDA):
39.375 kDA

Genomic Context


Human

Location:	4q35.2
Sequence:	4; NC_000004.12 (186532769..186555567, complement)

Tissue Specificity

Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Dysequilibrium Syndrome
Malignant Neoplasm Of Breast
Adolescent Idiopathic Scoliosis
Carcinoma
Malignant Neoplasms
Neoplasms
Scoliosis, Unspecified
Diabetes Mellitus
Mammary Neoplasms
Diabetes Mellitus, Non-insulin-dependent
Cytogenetic Abnormality
Schizophrenia

Child Development Disorders, Pervasive
Autistic Disorder
Autism Spectrum Disorders
Cholangiocarcinoma
Unbalanced Translocation
Mouth Neoplasms
Dyskinetic Syndrome

Interacting Proteins

CALR
HTR2C
MTNR1B
RGS20
TMEM33

Pathways

Secretion
Insulin Secretion
Mating
Cell Proliferation
Circadian Rhythm
Aging
Oocyte Maturation
Glucose Homeostasis
Methylation
Regulation Of Glucose Homeostasis

Cell Growth
Estrus
Rna Interference
Hormone Secretion

PTMs

Cleavage

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTNR1A

References

PMID: 7946354 by Reppert S.M., et al. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses.

PMID: 10471411 by Ebisawa T., et al. Alleic variants of human melatonin 1a receptor: function and prevalence in subjects with circadian rhythm sleep disorders.