Max-interacting protein 1 Antibodies

AND MXI1 ELISA kits, Max-interacting protein 1 Proteins

Many biological assays use antibodies to detect Max-interacting protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Max-interacting protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Max-interacting protein 1 antibodies...

We validate the specificity of these antibodies to Max-interacting protein 1 by testing them on tissues known to express MXI1 positively and negatively. Browse below to find the MXI1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Max-interacting protein 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MXI1 Western Blot Guide

MXI1 Infographic by Boster Bio

All MXI1 Products

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Specificity

Applications

Price

MXI1 (NM_130439) Human Over-expression Lysate

MXI1 Human Over-expression Lysates NM_001008541

Human

$628
Cat # LS004601
20 µg, 100 µg

Anti-Max-interacting protein 1 MXI1 Antibody

Western blot analysis of extracts of Mouse brain, using MXI1 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A08708
100ul

MXI1 Overview

Facts about Max-interacting protein 1.

MXI1 3D structure. Source: alphafold

Max-interacting protein 1 (MXI1)

Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'.

MXI1 thus antagonizes MYC transcriptional activity by competing for MAX. .

Gene Information

Human
Gene Name:	MXI1
Uniprot:	P50539
Entrez:	4601

Family

Belongs to:

No superfamily

Alternative Names

BHLHC11; Class C basic helix-loop-helix protein 11; MAD2; MAX dimerization protein 2; MAX interacting protein 1; MAX interactor 1bHLHc11MAD2; max-interacting protein 1; Max-related transcription factor; MGC43220; MXD2; MXI; Mxi1; MXI-WR

Molecular Weight

Mass (kDA):
26.062 kDA

Genomic Context


Human

Location:	10q25.2
Sequence:	10; NC_000010.11 (110207605..110287365)

Tissue Specificity

High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Carcinoma
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Malignant Paraganglionic Neoplasm
Adenocarcinoma
Leukemia
Skin Neoplasms
Melanoma
Hypoxia
Metaplastic Cell Transformation

Growth Arrest
Glioblastoma
Neuroblastoma
Lymphohistiocytosis, Hemophagocytic
Hyperplasia
Neoplasm Metastasis
Lung Neoplasms

Interacting Proteins

CALCOCO2
ENTPD5
KRT40
KRTAP10-5
KRTAP10-7

KRTAP10-8
KRTAP10-9
MAX
NOTCH2NL
USHBP1

Pathways

Cell Cycle
Cell Proliferation
Cell Growth
Pathogenesis
Cell Death
Localization
S Phase
Cell Cycle Arrest
Cell Adhesion
Programmed Cell Death
Translation
Response To Hypoxia
Glycolysis

Tissue Homeostasis
Transport
Granulocyte Differentiation
Cell Activation
Dna Hypermethylation
T Cell Activation
Neurogenesis

PTMs

Phosphorylation
Deacetylation

Methylation
Cleavage

Dephosphorylation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MXI1

References

PMID: 8425219 by Zervos A.S., et al. Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites.

PMID: 8838813 by Wechsler D.S., et al. Genomic organization of human MXI1, a putative tumor suppressor gene.