This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Myosin regulatory light chain 2, ventricular/cardiac muscle isoform.
These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a way to fine-tune myofilament calcium sensitivity to induce (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).
| Human | |
|---|---|
| Gene Name: | MYL2 |
| Uniprot: | P10916 |
| Entrez: | 4633 |

| Belongs to: |
|---|
| No superfamily |

cardiac ventricular myosin light chain 2; CMH10myosin light chain 2; DKFZp779C0562; MLC2; MLC-2; MLC-2v; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2
Mass (kDA):
18.789 kDA

| Human | |
|---|---|
| Location: | 12q24.11 |
| Sequence: | 12; NC_000012.12 (110910845..110920579, complement) |
Cytoplasm, myofibril, sarcomere, A band.





PMID: 2704627 by Libera L.D., et al. Isolation and nucleotide sequence of the cDNA encoding human ventricular myosin light chain 2.
PMID: 8287067 by Wadgaonkar R., et al. Interaction of a conserved peptide domain in recombinant human ventricular myosin light chain-2 with myosin heavy chain.