MYO7B Antibodies

AND MYO7B ELISA kits, MYO7B Proteins

Many biological assays use antibodies to detect MYO7B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MYO7B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MYO7B antibodies...

We validate the specificity of these antibodies to MYO7B by testing them on tissues known to express MYO7B positively and negatively. Browse below to find the MYO7B antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYO7B Infographic by Boster Bio

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MYO7B Overview

Facts about Unconventional myosin-VIIb.

MYO7B 3D structure. Source: alphafold

Unconventional myosin-VIIb (MYO7B)

Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.

As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli business and length. May link the complex to the actin core bundle of microvilli (Probable).

Gene Information

Human
Gene Name:	MYO7B
Uniprot:	Q6PIF6
Entrez:	4648

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

Unconventional myosin-VIIb

Molecular Weight

Mass (kDA):
241.599 kDA

Genomic Context


Human

Location:	2q14.3
Sequence:	2; NC_000002.12 (127535689..127637728)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection, microvillus. Enriched in the microvilli of the intestinal brush border.

Interacting Proteins

CDHR2

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYO7B

References

PMID: 8022818 by Bement W.M., et al. Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

PMID: 24725409 by Crawley S.W., et al. Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion.