MYT1 Antibodies

AND MYT1 ELISA kits, MYT1 Proteins

Many biological assays use antibodies to detect MYT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MYT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MYT1 antibodies...

We validate the specificity of these antibodies to MYT1 by testing them on tissues known to express MYT1 positively and negatively. Browse below to find the MYT1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYT1 Infographic by Boster Bio

All MYT1 Products

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MYT1 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HeLa cells

Human

ELISA

$480
Cat # EKC1394
1 kit, containing one 96-well plate and all necessary reagents

Anti-MYT1 Antibody Picoband®

Western blot analysis of MYT1 using anti-MYT1 antibody (A04210-1)

Human, Mouse, Rat

$370
Cat # A04210-1
100 μg/vial

MYT1 Overview

Facts about Myelin transcription factor 1.

MYT1 3D structure. Source: alphafold

Myelin transcription factor 1 (MYT1)

Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS.

May regulate a crucial transition point in oligodendrocyte lineage growth by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up- regulation of myelin gene transcription. .

Gene Information

Human
Gene Name:	MYT1
Uniprot:	Q01538
Entrez:	4661

Family

Belongs to:

MYT1 family

Alternative Names

C20orf36; MTF1proteolipid protein binding protein; myelin transcription factor 1; Myelin transcription factor I; MyT1; MyTI; MYTIKIAA0835; PLPB1KIAA1050; Proteolipid protein-binding protein

Molecular Weight

Mass (kDA):
122.329 kDA

Genomic Context


Human

Location:	20q13.33
Sequence:	20; NC_000020.11 (64164452..64242253)

Tissue Specificity

Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Nervousness
Pelizaeus-merzbacher Disease
Neoplasms
Sclerosis
Multiple Sclerosis
Diffuse Cerebral Sclerosis Of Schilder
Paraplegia
Sex Chromosome Aberrations
Demyelination
Spastic Paraplegia
Carcinoma

Diabetes Mellitus
Cell Transformation, Neoplastic
Encephalomyelitis, Western Equine
Melanoma
Haploinsufficiency
Major Depressive Disorder

Pathways

Cell Cycle
Mitosis
Meiosis
Myelination
Oocyte Maturation
M Phase
Interphase
Cell Division
Cell Differentiation
Cell Cycle Arrest
Translation
Prophase
Localization

Cell Proliferation
S Phase
Meiosis I
Cell Death
Dna Replication
Regeneration
Hyperphosphorylation

PTMs

Phosphorylation
Dephosphorylation

Reduction
Cleavage

Methylation

Research Areas

Neuroscience
Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYT1

References

PMID: 1280325 by Kim J.G., et al. Novel member of the zinc finger superfamily: a C2-HC finger that recognizes a glia-specific gene.

PMID: 8530187 by Armstrong R.C., et al. Expression of myelin transcription factor I (MyTI), a 'zinc-finger' DNA-binding protein, in developing oligodendrocytes.