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- Table of Contents
Facts about Homeobox protein MOX-1.
Activates expression of NKX3-2 from the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation.
| Human | |
|---|---|
| Gene Name: | MEOX1 |
| Uniprot: | P50221 |
| Entrez: | 4222 |

| Belongs to: |
|---|
| No superfamily |

homeobox protein MOX-1; mesenchyme homeobox 1MOX1mesenchyme homeo box 1
Mass (kDA):
27.997 kDA

| Human | |
|---|---|
| Location: | 17q21.31 |
| Sequence: | 17; NC_000017.11 (43640389..43661977, complement) |
Nucleus. Cytoplasm. Localizes predominantly in the nucleus.





PMID: 7987315 by Futreal P.A., et al. Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture.
PMID: 23290072 by Mohamed J.Y., et al. Mutations in MEOX1, encoding mesenchyme homeobox 1, cause Klippel- Feil anomaly.