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- Table of Contents
LRP chaperone MESD Antibodies
AND MESD ELISA kits, LRP chaperone MESD Proteins
Many biological assays use antibodies to detect LRP chaperone MESD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRP chaperone MESD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRP chaperone MESD antibodies...
Designing a Western blot for LRP chaperone MESD? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MESD Western Blot GuideMESD Infographic by Boster Bio
All MESD Products
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Specificity
Applications
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MESD Overview
Facts about LRP chaperone MESD.
LRP chaperone MESD (MESD)
Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway via chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane.
Essential for specification of embryonic polarity and mesoderm induction. Plays an important role in neuromuscular junction (NMJ) formation by promoting cell- surface expression of LRP4 (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | MESD |
| Uniprot: | Q14696 |
| Entrez: | 23184 |
Family
| Belongs to: |
|---|
| MESD family |
Alternative Names
LRP chaperone MESD
Molecular Weight
Mass (kDA):
26.077 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q25.1 |
| Sequence: | 15; NC_000015.10 (80946289..80989819, complement) |
Subcellular Localizations
Endoplasmic reticulum. Released from apoptotic cells and shed photoreceptor outer segments.
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MESD
bosterbio.com/bosterbio-gene-info-cards/MESD
References
PMID: 15014448 by Culi J., et al. Boca-dependent maturation of beta-propeller/EGF modules in low- density lipoprotein receptor proteins.
PMID: 17488095 by Koduri V., et al. Requirement for natively unstructured regions of mesoderm development candidate 2 in promoting low-density lipoprotein receptor-related protein 6 maturation.