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- Table of Contents
NGFI-A-binding protein 2 Antibodies
AND NAB2 ELISA kits, NGFI-A-binding protein 2 Proteins
Many biological assays use antibodies to detect NGFI-A-binding protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NGFI-A-binding protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NGFI-A-binding protein 2 antibodies...
Designing a Western blot for NGFI-A-binding protein 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NAB2 Western Blot GuideNAB2 Infographic by Boster Bio
All NAB2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02873-3
100 μg/vial
Cat # A02873-3
100 μg/vial
Human, Mouse
ELISA
$480
Cat # EKC1830
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1830
1 kit, containing one 96-well plate and all necessary reagents
NAB2 Overview
Facts about NGFI-A-binding protein 2.
NGFI-A-binding protein 2 (NAB2)
Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NAB2 |
| Uniprot: | Q15742 |
| Entrez: | 4665 |
Family
| Belongs to: |
|---|
| NAB family |
Alternative Names
EGR-1-binding protein 2; MADEREGR1 binding protein 2; Melanoma-associated delayed early response protein; MGC75085; NGFI-A binding protein 2 (EGR1 binding protein 2); NGFI-A-binding protein 2; Protein MADER
Molecular Weight
Mass (kDA):
56.594 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.3 |
| Sequence: | 12; NC_000012.12 (57089114..57095476) |
Tissue Specificity
Widely expressed at low levels. Highly expressed in melanoma cell lines.
Subcellular Localizations
Nucleus. Isoform 2 is not localized to the nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Malignant Neoplasm Of Prostate
- Inflammation
- Nervousness
- Melanoma
- Tumor Angiogenesis
- Prostatic Neoplasms
- Peripheral Neuropathy
- Fibrosis
- Congenital Hypomyelinating Neuropathy
Interacting Proteins
- AES
- CWF19L2
- GCC1
- JAKMIP2
- KRTAP10-8
- LENG1
- MCM7
- MORF4L1
- NEDD9
- NME7
Pathways
- Nuclear Export
- Localization
- Myelination
- Translation
- Transport
- Nuclear Import
- Pathogenesis
- Angiogenesis
- Rna Processing
- Nuclear Transport
- Chromatin Remodeling
- Cell Proliferation
- Hindbrain Development
PTMs
- Phosphorylation
- Methylation
- Cleavage
Research Areas
- Neuroscience
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAB2
bosterbio.com/bosterbio-gene-info-cards/NAB2
References
PMID: 8668170 by Svaren J., et al. NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli.
PMID: 8649813 by Kirsch K.H., et al. Mader: a novel nuclear protein over expressed in human melanomas.