NCOA4 Antibodies

AND NCOA4 ELISA kits, NCOA4 Proteins

Many biological assays use antibodies to detect NCOA4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NCOA4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NCOA4 antibodies...

We validate the specificity of these antibodies to NCOA4 by testing them on tissues known to express NCOA4 positively and negatively. Browse below to find the NCOA4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for NCOA4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NCOA4 Western Blot Guide

NCOA4 Infographic by Boster Bio

All NCOA4 Products

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Product

Figures

Specificity

Applications

Price

Anti-NCOA4 Antibody Picoband®

Western blot analysis of NCOA4 using anti-NCOA4 antibody (A04368-3)

Flow Cytometry analysis of HL-60 cells using anti-NCOA4 antibody (A04368-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A04368-3
100 μg/vial

NCOA4 (NM_001145262) Human Over-expression Lysate

NCOA4 Human Over-expression Lysates NM_001145262

Human

$628
Cat # LS008031
20 µg, 100 µg

NCOA4 (NM_005437) Human Recombinant Protein

Coomassie blue staining of purified NCOA4 protein

$1062
Cat # PROTQ13772
20 µg

NCOA4 Overview

Facts about Nuclear receptor coactivator 4.

NCOA4 3D structure. Source: alphafold

Nuclear receptor coactivator 4 (NCOA4)

Improves the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.

Gene Information

Human
Gene Name:	NCOA4
Uniprot:	Q13772
Entrez:	8031

Family

Belongs to:

No superfamily

Alternative Names

Androgen receptor coactivator 70 kDa protein; Androgen receptor-associated protein of 70 kDa; ARA70RFGret fused; DKFZp762E1112; ELE1NCoA-4; nuclear receptor coactivator 4,70 kDa AR-activator; PTC3RET-activating gene ELE1; Ret-activating protein ELE1,70 kDa androgen receptor coactivator

Molecular Weight

Mass (kDA):
69.726 kDA

Genomic Context


Human

Location:	10q11.22
Sequence:	10; NC_000010.11 (46005088..46030714, complement)

Tissue Specificity

Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Prostate
Carcinoma
Thyroid Neoplasm
Prostatic Neoplasms
Carcinoma, Papillary
Malignant Neoplasm Of Thyroid
Papillary Thyroid Carcinoma
Cell Transformation, Neoplastic
Neoplasms, Radiation-induced
Malignant Paraganglionic Neoplasm
Neoplasm Metastasis

Malignant Neoplasm Of Breast
Mammary Neoplasms
Hyperplasia
Adenoma
Ret/ptc Rearrangement
Neoplasm Invasiveness
Carcinogenesis

Pathways

Cell Proliferation
Cell Growth
Receptor Transactivation
Cell Cycle
Pathogenesis
Regulation Of Gene Expression
Interphase
Localization
Reproductive System Development
Spermatogenesis
Cell Division
System Development
Organ Development

Angiogenesis
Secretion
Proteolysis
Cytokine Secretion
Mammary Gland Development
Vasculogenesis
Liver Development

PTMs

Phosphorylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NCOA4

References

PMID: 8643607 by Yeh S., et al. Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

PMID: 8290261 by Santoro M., et al. Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma.