NDUFS8 Antibodies

AND NDUFS8 ELISA kits, NDUFS8 Proteins

Many biological assays use antibodies to detect NDUFS8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFS8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFS8 antibodies...

We validate the specificity of these antibodies to NDUFS8 by testing them on tissues known to express NDUFS8 positively and negatively. Browse below to find the NDUFS8 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDUFS8 Infographic by Boster Bio

All NDUFS8 Products

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Specificity

Applications

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Anti-NDUFS8 Antibody

Western blot analysis of extracts of various cell lines, using NDUFS8 antibody at 1:3000 dilution

Immunofluorescence analysis of L929 cells using NDUFS8 Polyclonal Antibody at dilution of 1:100

Mouse

IF, ICC, WB

$405
Cat # A08275
100ul

Anti-NDUS8 NDUFS8 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08275-1
100ul

Anti-NDUFS8 Antibody Picoband®

2 Citations

Western blot analysis of NDUFS8 using anti-NDUFS8 antibody (A08275-2)

IHC analysis of NDUFS8 using anti-NDUFS8 antibody (A08275-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A08275-2
100 μg/vial

NDUFS8 (NM_002496) Human Over-expression Lysate

Human

$628
Cat # LS004728
20 µg, 100 µg

NDUFS8 Overview

Facts about NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial.

NDUFS8 3D structure. Source: alphafold

NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (NDUFS8)

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is thought to belong to the minimum assembly required for catalysis. Sophisticated I works in the transfer of electrons from NADH to the respiratory chain.

The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone.

Gene Information

Human
Gene Name:	NDUFS8
Uniprot:	O00217
Entrez:	4728

Family

Belongs to:

complex I 23 kDa subunit family

Alternative Names

CI-23k; CI23KD; CI-23kD; complex I 23kDa subunit; Complex I-23kD; EC 1.6.5.3; EC 1.6.99.3; EC 1.6.99.5; NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Qreductase); NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Qreductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY subunit; TYKY

Molecular Weight

Mass (kDA):
23.705 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (68030681..68036644)

Subcellular Localizations

Mitochondrion.

Diseases

Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
Leigh Disease
Mitochondrial Diseases
Carcinoma
Neurodegenerative Disorders
Malignant Neoplasm Of Adrenal Cortex
Neoplasms
Adenoma
Mutation Abnormality
Weakness
Ataxia
Tumors Of Adrenal Cortex

Malignant Neoplasm Of Liver
Parkinson Disease
Carcinogenesis
Severe Sepsis
Dysarthria
Malignant Neoplasms
Post-traumatic Stress Disorder

Pathways

Oxidative Phosphorylation
Transport
Pathogenesis
Secretion
Cell Proliferation
Gene Silencing
Electron Transport
Electron Transport Chain
Cortisol Secretion
Localization

Methylation
Cell Death
Dedifferentiation
Fatty Acid Oxidation
Rna Interference

PTMs

Phosphorylation

Oxidation

Nitration

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFS8

References

PMID: 9116042 by Procaccio V., et al. cDNA sequence and chromosomal localization of the NDUFS8 human gene coding for the 23 kDa subunit of the mitochondrial complex I.

PMID: 9666055 by de Sury R., et al. Genomic structure of the human NDUFS8 gene coding for the iron-sulfur TYKY subunit of the mitochondrial NADH:ubiquinone oxidoreductase.