Sialidase-2 Antibodies

AND NEU2 ELISA kits, Sialidase-2 Proteins

Many biological assays use antibodies to detect Sialidase-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sialidase-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sialidase-2 antibodies...

We validate the specificity of these antibodies to Sialidase-2 by testing them on tissues known to express NEU2 positively and negatively. Browse below to find the NEU2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NEU2 Infographic by Boster Bio

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Anti-Neuraminidase NEU2 Antibody

7 Q&As

Western blot analysis using Boster Immunochemical's Affinity Purified anti-Neu2 antibody to detect recombinant His tagged Neu-2 (1

Western blot analysis using Boster Immunochemical

Human

ELISA, IP, IHC, WB

$641
Cat # A06481
100ug

Anti-NEU2 Mouse Monoclonal Antibody [Clone ID: OTI4F4]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEU2 (Right lane) cDNA for 48 hrs and lysed

Anti-NEU2 mouse monoclonal antibody (M06481) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NEU2

Human

Flow Cytometry, IF, WB

$523
Cat # M06481
100 µl

NEU2 (NM_005383) Human Over-expression Lysate

Human

$628
Cat # LS004759
20 µg, 100 µg

Anti-NEU2 Antibody Picoband®

Western blot analysis of NEU2 using anti-NEU2 antibody (A06481-1)

Mouse, Rat

$370
Cat # A06481-1
100 μg/vial

NEU2 Overview

Facts about Sialidase-2.

NEU2 3D structure. Source: alphafold

Sialidase-2 (NEU2)

Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins, oligosaccharides and gangliosides. .

Gene Information

Human
Gene Name:	NEU2
Uniprot:	Q9Y3R4
Entrez:	4759

Family

Belongs to:

glycosyl hydrolase 33 family

Alternative Names

Cytosolic sialidase; EC 3.2.1.18; N-acetyl-alpha-neuraminidase 2; neuraminidase 2; SIAL2MGC129579; sialidase 2 (cytosolic sialidase); sialidase-2

Molecular Weight

Mass (kDA):
42.254 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (233032672..233035057)

Tissue Specificity

Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Influenza
Type I Mucolipidosis
Stomach Neoplasms
Influenza In Birds
Galactosialidosis
Atrophy
Cholera
Hypertrophy
Carcinogenesis
Neuraminidase 1 Deficiency
Tissue Adhesions

Pneumonia
Malignant Neoplasm Of Stomach
Leukemia
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Lymph Node
Infectious Mononucleosis
Malignant Neoplasm Of Breast

Interacting Proteins

NOTCH2NL

Pathways

Localization
Myoblast Differentiation
Cell Adhesion
Cell Proliferation
Monocyte Differentiation
Cell Activation
Response To Stress
Cell Migration
Glycosylation
Immune Response
Ovulation
Virulence
Muscle Atrophy

Endothelial Cell Migration
Macroautophagy
Muscle Hypertrophy
Cell Cycle
Cell Differentiation
Pathogenesis
Autophagy

PTMs

Carboxylation
Cleavage

Glycosylation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NEU2

References

PMID: 10191093 by Monti E., et al. Cloning and characterization of NEU2, a human gene homologous to rodent soluble sialidases.

PMID: 14613940 by Tringali C., et al. Properties of recombinant human cytosolic sialidase HsNEU2. The enzyme hydrolyzes monomerically dispersed GM1 ganglioside molecules.