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- Table of Contents
NFYB Antibodies
AND NFYB ELISA kits, NFYB Proteins
Many biological assays use antibodies to detect NFYB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NFYB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NFYB antibodies...
Designing an IHC experiment for NFYB? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NFYB IHC GuideNFYB Infographic by Boster Bio
All NFYB Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1697
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1697
1 kit, containing one 96-well plate and all necessary reagents
NFYB Overview
Facts about Nuclear transcription factor Y subunit beta.
Nuclear transcription factor Y subunit beta (NFYB)
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif located in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | NFYB |
| Uniprot: | P25208 |
| Entrez: | 4801 |
Family
| Belongs to: |
|---|
| NFYB/HAP3 subunit family |
Alternative Names
CAAT box DNA-binding protein subunit B; CBF-A; HAP3CBF-B; NF-YBCCAAT-binding transcription factor subunit A; Nuclear transcription factor Y subunit B; nuclear transcription factor Y subunit beta; nuclear transcription factor Y, beta; Transcription factor NF-Y, B subunit
Molecular Weight
Mass (kDA):
22.831 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q23.3 |
| Sequence: | 12; NC_000012.12 (104117086..104138241, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Leukemia
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Ataxia
- Swine Diseases
- Gait, Drop Foot
- Leukemia, Myelocytic, Acute
- Fibrosis
- Cardiovascular Diseases
- Myeloid Leukemia
Interacting Proteins
- AGTRAP
- DRAP1
- NFYA
- NFYC
- POLE4
- TP53
Pathways
- Cell Cycle
- Cell Proliferation
- Localization
- Transport
- Regulation Of Cell Cycle
- Aging
- Immune Response
- Cell Cycle Arrest
- Transcriptional Attenuation
- Senescence
- Methylation
PTMs
- Acetylation
- Phosphorylation
- Cleavage
Research Areas
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NFYB
bosterbio.com/bosterbio-gene-info-cards/NFYB
References
PMID: 1577736 by Li X.-Y., et al. Intron-exon organization of the NF-Y genes. Tissue-specific splicing modifies an activation domain.
PMID: 1549471 by Li X.-Y., et al. Evolutionary variation of the CCAAT-binding transcription factor NF- Y.