NADPH oxidase activator 1 Antibodies

AND NOXA1 ELISA kits, NADPH oxidase activator 1 Proteins

Many biological assays use antibodies to detect NADPH oxidase activator 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NADPH oxidase activator 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NADPH oxidase activator 1 antibodies...

We validate the specificity of these antibodies to NADPH oxidase activator 1 by testing them on tissues known to express NOXA1 positively and negatively. Browse below to find the NOXA1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NOXA1 Infographic by Boster Bio

All NOXA1 Products

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Specificity

Applications

Price

Anti-NOXA1 Antibody Picoband®

1 Citations 4 Q&As

Western blot analysis of NOXA1 using anti-NOXA1 antibody (PPA1930)

Human

$370
Cat # PA1930
100 μg/vial

NOXA1 (NM_006647) Human Over-expression Lysate

Human

$628
Cat # LS010811
20 µg, 100 µg

Anti-NOXA1 Antibody Picoband®

Western blot analysis of NOXA1 using anti-NOXA1 antibody (A04679)

Human

ELISA, WB

$370
Cat # A04679
100 μg/vial

NOXA1 Overview

Facts about NADPH oxidase activator 1.

NOXA1 3D structure. Source: alphafold

NADPH oxidase activator 1 (NOXA1)

Functions as an activator of NOX1, a superoxide- generating NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction.

May also activate CYBB/gp91phox and NOX3. .

Gene Information

Human
Gene Name:	NOXA1
Uniprot:	Q86UR1
Entrez:	10811

Family

Belongs to:

NCF2/NOXA1 family

Alternative Names

Antigen NY-CO-31; FLJ25475; inhibitory NADPH oxidase activator 1; MGC131800; NADPH oxidase activator 1; NCF2-like protein; NOX activator 1; NY-CO-31; p51NOX; p51-nox; P67phox-like factor; SDCCAG31; serologically defined colon cancer antigen 31

Molecular Weight

Mass (kDA):
50.933 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (137423372..137434406)

Tissue Specificity

Widely expressed. Detected in pancreas, liver, kidney, spleen, prostate, small intestine and colon.

Subcellular Localizations

Cytoplasm. Cell membrane. Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Tumor Of Colon
Hypoxia
Carcinoma
Fibrosis
Tumor Angiogenesis
Inflammation
Colonic Neoplasms
Cardiovascular Diseases
Anoxia
Atherosclerosis
Hypertensive Disease

Vascular Diseases
Dyslipidemias
Ataxia
Hepatitis C, Chronic
Neoplasm Invasiveness
Injury To Liver
Posttransfusion Purpura

Interacting Proteins

RIMBP3

Pathways

Localization
Cell Death
Phagocytosis
Cell Proliferation
Pathogenesis
Respiratory Burst
Transport
Angiogenesis
Secretion
Cell Adhesion
Protein Phosphorylation
Cell Activation
Hyperphosphorylation

Proteolysis
Immune Response
Pigmentation
Superoxide Anion Generation
Regulation Of Lipid Binding
Reverse Transcription
Translation

PTMs

Phosphorylation
Glycosylation

Acetylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOXA1

References

PMID: 12657628 by Geiszt M., et al. Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells.

PMID: 12716910 by Takeya R., et al. Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases.