Npas3 Antibodies

AND Npas3 ELISA kits, Npas3 Proteins

Many biological assays use antibodies to detect Npas3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Npas3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Npas3 antibodies...

We validate the specificity of these antibodies to Npas3 by testing them on tissues known to express Npas3 positively and negatively. Browse below to find the Npas3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Npas3 Infographic by Boster Bio

All Npas3 Products

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Specificity

Applications

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Anti-NPAS3 Antibody

Western blot analysis of NPAS3 in SK-N-SH cell lysate with NPAS3 antibody at (A) 0

Immunohistochemistry of NPAS3 in human brain tissue with NPAS3 antibody at 5 μg/mL

Immunofluorescence of NPAS3 in human brain tissue with NPAS3 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A10668
0.1 mg

NPAS3 (NM_022123) Human Over-expression Lysate

Human

$960
Cat # LS064067
20 µg, 100 µg

Npas3 Overview

Facts about Neuronal PAS domain-containing protein 3.

Neuronal PAS domain-containing protein 3 (Npas3)

May play a broad role in neurogenesis. May control regulatory pathways related to schizophrenia and to psychotic illness.

Gene Information

Mouse
Gene Name:	Npas3
Uniprot:	Q9QZQ0
Entrez:	27386

Family

Belongs to:

No superfamily

Alternative Names

Basic-helix-loop-helix-PAS protein MOP6; BHLHE12; bHLHe12FLJ11605; Class E basic helix-loop-helix protein 12; Member of PAS protein 6; MOP6FLJ10003; neuronal PAS domain protein 3; neuronal PAS domain-containing protein 3; Neuronal PAS3; PAS domain-containing protein 6; PASD6FLJ11138

Molecular Weight

Mass (kDA):
100.458 kDA

Genomic Context


Mouse

Location:	12\|12 C1
Sequence:	12;

Tissue Specificity

Detected exclusively in adult brain in inhibitory interneurons.

Diseases

Schizophrenia
Mental Disorders
Psychotic Disorders
Depressive Disorder
Bipolar Disorder
Haploinsufficiency
Major Depressive Disorder
Nervousness
Cytogenetic Abnormality
Malnutrition
Neoplasms
Chromosome Breakage

Holoprosencephaly
Mood Disorders
Sclerosis
Learning Disorders
Microphthalmos
Learning Disabilities
Dementia

Pathways

Neurogenesis
Cell Proliferation
Prepulse Inhibition
Brain Development
Response To Iloperidone
Circadian Rhythm
Aging
Lung Development
Neuron Differentiation
Neuron Death
Localization
Startle Response
Stem Cell Proliferation

Cellular Localization
Neural Precursor Cell Proliferation
Cell Cycle
Cell Differentiation
Regulation Of Cell Differentiation
Pathogenesis
Glycolysis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Npas3

References

PMID: 10534623 by Brunskill E.W., et al. Characterization of Npas3, a novel basic helix-loop-helix PAS gene expressed in the developing mouse nervous system.

PMID: 15347806 by Erbel-Sieler C., et al. Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors.