Neuropeptide FF receptor 2 (NPFFR2)

Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also called morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands.

This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. .