NPR3 Antibodies

AND NPR3 ELISA kits, NPR3 Proteins

Many biological assays use antibodies to detect NPR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NPR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NPR3 antibodies...

We validate the specificity of these antibodies to NPR3 by testing them on tissues known to express NPR3 positively and negatively. Browse below to find the NPR3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for NPR3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NPR3 Western Blot Guide

NPR3 Infographic by Boster Bio

All NPR3 Products

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Product

Figures

Specificity

Applications

Price

Anti-NPRC Rabbit Monoclonal Antibody

1 Citations

Western blot analysis of NPRC using anti-NPRC antibody (M03589)

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M03589
100 μl

Anti-Natriuretic Peptide Receptor C Antibody

Human

$299
Cat # M03589-1
50 µl

Natriuretic Peptide Receptor C (NPR3) (NM_000908) Human Over-expression Lysate

Human

$960
Cat # LS004883
20 µg, 100 µg

NPR3 Overview

Facts about Atrial natriuretic peptide receptor 3.

NPR3 3D structure. Source: alphafold

Atrial natriuretic peptide receptor 3 (NPR3)

Receptor for the natriuretic peptide hormones, binding with comparable affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May serve as a clearance receptor for NPPA, NPPB and NPPC, regulating their regional concentrations and effects.

May modulate diuresis, blood pressure and skeletal growth. Does not have guanylate cyclase activity.

Gene Information

Human
Gene Name:	NPR3
Uniprot:	P17342
Entrez:	4883

Family

Belongs to:

ANF receptor family

Alternative Names

ANP-C; ANPR-C; ANPRCFLJ14054; Atrial natriuretic peptide clearance receptor; atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; C5orf23; chromosome 5 open reading frame 23; GUCY2B; lgj; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptidereceptor C); NPR3; NPRC; NPR-C; stri

Molecular Weight

Mass (kDA):
59.808 kDA

Genomic Context


Human

Location:	5p13.3
Sequence:	5; NC_000005.10 (32689076..32791724)

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Hypertensive Disease
Neoplasms
Dwarfism
Medulloblastoma
Diabetes Mellitus
Hypertrophy
Cardiovascular Diseases
Cerebrovascular Accident
Ischemic Stroke
Obesity
Sclerosis
Learning Disorders
Primary Lateral Sclerosis

Dementia
Amyotrophic Lateral Sclerosis
Carcinoma
Congenital Anomaly Of Face
Immunologic Deficiency Syndromes
Dysplasia
Fibrosis

Pathways

Systemic Acquired Resistance
Cell Cycle
Endochondral Bone Growth
Cell Proliferation
Localization
Disease Resistance
Excretion
Autophagy
Cell Adhesion
Muscle Cell Proliferation
Programmed Cell Death
Ossification
Regulation Of Autophagy

Chromosome Segregation
Diuresis
Endothelial Cell Proliferation
Chondrocyte Proliferation
Wound Healing
Smooth Muscle Cell Proliferation
Endochondral Ossification

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPR3

References

PMID: 2162522 by Lowe D.G., et al. cDNA sequence of the human atrial natriuretic peptide clearance receptor.

PMID: 2169733 by Porter J.G., et al. Isolation and functional expression of the human atrial natriuretic peptide clearance receptor cDNA.