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- Table of Contents
Neurturin Antibodies
AND NRTN ELISA kits, Neurturin Proteins
Many biological assays use antibodies to detect Neurturin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neurturin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neurturin antibodies...
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NRTN Infographic by Boster Bio
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NRTN Overview
Facts about Neurturin.
Neurturin (NRTN)
Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS.
Might control the size of non-neuronal cell population such as haemopoietic cells. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NRTN |
| Uniprot: | Q99748 |
| Entrez: | 4902 |
Family
| Belongs to: |
|---|
| TGF-beta family |
Alternative Names
Neurturin; NRTN; NTN
Molecular Weight
Mass (kDA):
22.405 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (5805387..5828324) |
Subcellular Localizations
Secreted.
Diseases
- Nervousness
- Parkinson Disease
- Nerve Degeneration
- Neoplasms
- Hirschsprung Disease
- Secondary Parkinson Disease
- Crest Syndrome
- Neurodegenerative Disorders
- Neuroblastoma
- Retinal Degeneration
- Endocrine Gland Neoplasms
- Multiple Endocrine Neoplasia Type 2a
Pathways
- Innervation
- Cell Death
- Localization
- Regeneration
- Neuroprotection
- Pathogenesis
- Cell Proliferation
- Secretion
- Transport
- Programmed Cell Death
- Spermatogenesis
- System Development
- Neuron Development
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NRTN
bosterbio.com/bosterbio-gene-info-cards/NRTN
References
PMID: 8945474 by Kotzbauer P.T., et al. Neurturin, a relative of glial-cell-line-derived neurotrophic factor.
PMID: 9700200 by Doray B., et al. Mutation of the RET ligand, neurturin, supports multigenic inheritance in Hirschsprung disease.