Cytosolic Fe-S cluster assembly factor NUBP1 (NUBP1)

Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machines (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874).

The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to goal apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity).