Naip5 Antibodies

AND Naip5 ELISA kits, Naip5 Proteins

Many biological assays use antibodies to detect Naip5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Naip5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Naip5 antibodies...

We validate the specificity of these antibodies to Naip5 by testing them on tissues known to express Naip5 positively and negatively. Browse below to find the Naip5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Naip5 Infographic by Boster Bio

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Naip5 Overview

Facts about Baculoviral IAP repeat-containing protein 1e.

Naip5 3D structure. Source: alphafold

Baculoviral IAP repeat-containing protein 1e (Naip5)

Sensor part of the NLRC4 inflammasome that specifically recognizes and binds flagellin from pathogenic bacteria such as Legionella or Salmonella (PubMed:12526741, PubMed:21874021, PubMed:21918512, PubMed:29146805, PubMed:29182158). Association of pathogenic bacteria proteins drives in turn drive assembly and activation of the NLRC4 inflammasome, promoting caspase-1 activation, cytokine production and macrophage pyroptosis (PubMed:21874021, PubMed:21918512, PubMed:29146805, PubMed:29182158).

The NLRC4 inflammasome is triggered as part of the innate immune response to a range of intracellular bacteria. The NLRC4 inflammasome senses Gram- negative bacteria such as L.

Gene Information

Mouse
Gene Name:	Naip5
Uniprot:	Q9R016
Entrez:	17951

Family

Belongs to:

No superfamily

Alternative Names

Baculoviral IAP repeat-containing protein 1e

Molecular Weight

Mass (kDA):
159.839 kDA

Genomic Context


Mouse

Location:	13 D1\|13 53.05 cM
Sequence:	13;

Tissue Specificity

Detected in macrophages (at protein level).

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Naip5

References

PMID: 10501978 by Huang S., et al. The mouse Naip gene cluster on chromosome 13 encodes several distinct functional transcripts.

PMID: 10486205 by Endrizzi M., et al. Comparative sequence analysis of the mouse and human Lgn1/SMA interval.