Naip6 Antibodies

AND Naip6 ELISA kits, Naip6 Proteins

Many biological assays use antibodies to detect Naip6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Naip6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Naip6 antibodies...

We validate the specificity of these antibodies to Naip6 by testing them on tissues known to express Naip6 positively and negatively. Browse below to find the Naip6 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Naip6 Infographic by Boster Bio

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Naip6 Overview

Facts about Baculoviral IAP repeat-containing protein 1f.

Naip6 3D structure. Source: alphafold

Baculoviral IAP repeat-containing protein 1f (Naip6)

Sensor component of the NLRC4 inflammasome that specifically recognizes and binds flagellin from pathogenic bacteria. Association of pathogenic bacteria proteins drives in turn drive assembly and activation of the NLRC4 inflammasome, promoting caspase-1 activation, cytokine production and macrophage pyroptosis.

The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria (PubMed:21874021). The NLRC4 inflammasome senses Gram-negative germs like L.

Gene Information

Mouse
Gene Name:	Naip6
Uniprot:	Q9JIB6
Entrez:	17952

Family

Belongs to:

No superfamily

Alternative Names

Baculoviral IAP repeat-containing protein 1f

Molecular Weight

Mass (kDA):
159.866 kDA

Genomic Context


Mouse

Location:	13 D1\|13 53.09 cM
Sequence:	13;

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Naip6

References

PMID: 10958627 by Endrizzi M.G., et al. Genomic sequence analysis of the mouse Naip gene array.

PMID: 12526741 by Wright E.K., et al. Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila.