OAZ2 Antibodies

AND OAZ2 ELISA kits, OAZ2 Proteins

Many biological assays use antibodies to detect OAZ2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OAZ2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OAZ2 antibodies...

We validate the specificity of these antibodies to OAZ2 by testing them on tissues known to express OAZ2 positively and negatively. Browse below to find the OAZ2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OAZ2 Infographic by Boster Bio

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Anti-OAZ2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A12935
100ul

OAZ2 Overview

Facts about Ornithine decarboxylase antizyme 2.

OAZ2 3D structure. Source: alphafold

Ornithine decarboxylase antizyme 2 (OAZ2)

Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the operational ODC homodimers.

Does not target the ODC monomers for degradation, which allows a protein synthesis-independent recovery of ODC activity (PubMed:17900240). Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol (By similarity).

Gene Information

Human
Gene Name:	OAZ2
Uniprot:	O95190
Entrez:	4947

Family

Belongs to:

ODC antizyme family

Alternative Names

AZ2; ODC-Az 2; ornithine decarboxylase antizyme 2

Molecular Weight

Mass (kDA):
21.011 kDA

Genomic Context


Human

Location:	15q22.31
Sequence:	15; NC_000015.10 (64687574..64703281, complement)

Subcellular Localizations

Nucleus.

Diseases

Neuroblastoma
Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Embryonal Carcinoma
Male Infertility
Pediatric Neoplasm
Oncogene Deregulation

Infertility
Cancer Patients And Suicide And Depression
Patient Dependence On

Pathways

Translation
Cell Differentiation
Neuroblast Proliferation
Spermatogenesis
Oncogenesis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OAZ2

References

PMID: 9782076 by Ivanov I.P., et al. A second mammalian antizyme: conservation of programmed ribosomal frameshifting.

PMID: 10352227 by Zhou J., et al. Structure of human ornithine decarboxylase antizyme 2 gene.