Protein Mis18-beta Antibodies

AND OIP5 ELISA kits, Protein Mis18-beta Proteins

Many biological assays use antibodies to detect Protein Mis18-beta, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Mis18-beta in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Mis18-beta antibodies...

We validate the specificity of these antibodies to Protein Mis18-beta by testing them on tissues known to express OIP5 positively and negatively. Browse below to find the OIP5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OIP5 Infographic by Boster Bio

All OIP5 Products

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Anti-OIP5 Mouse Monoclonal Antibody [Clone ID: OTI1F1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OIP5 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of MCF7 cell lysate (35ug) by using anti-OIP5 monoclonal antibody (1:500)

Human

IHC, WB

$523
Cat # M07819
100 µl

OIP5 (NM_007280) Human Over-expression Lysate

Human

$628
Cat # LS011339
20 µg, 100 µg

Anti-OIP5 Antibody Picoband®

Western blot analysis of OIP5 using anti-OIP5 antibody (A07819)

Flow Cytometry analysis of HepG2 cells using anti-OIP5 antibody (A07819)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A07819
100 µg/vial

Anti-Oip5 Antibody Picoband®

Western blot analysis of Oip using anti-Oip antibody (A07819-1)

Mouse, Rat

ELISA, WB

$370
Cat # A07819-1
100 µg/vial

OIP5 Overview

Facts about Protein Mis18-beta.

OIP5 3D structure. Source: alphafold

Protein Mis18-beta (OIP5)

Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. .

Gene Information

Human
Gene Name:	OIP5
Uniprot:	O43482
Entrez:	11339

Family

Belongs to:

mis18 family

Alternative Names

Cancer/testis antigen 86; CT865730547N13Rik; hMIS18beta; LAP2alpha interactor-25; LINT-25; MIS18B; MIS18beta; OIP-5; Opa interacting protein 5; Opa-interacting protein 5; protein Mis18-beta

Molecular Weight

Mass (kDA):
24.691 kDA

Genomic Context


Human

Location:	15q15.1
Sequence:	15; NC_000015.10 (41309268..41332621, complement)

Subcellular Localizations

Nucleus. Chromosome. Chromosome, centromere. Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.

Diseases

Malignant Neoplasms
Neoplasms
Stomach Neoplasms
Carcinogenesis
Malignant Neoplasm Of Stomach
Adenocarcinoma
Malignant Squamous Cell Neoplasm
Lung Neoplasms
Malignant Neoplasm Of Esophagus
Malignant Neoplasm Of Lung
Carcinoma
Leukemia, Myelocytic, Acute

Retinoblastoma
Myeloid Leukemia
Colorectal Neoplasms
Leukemia
Hematological Disease
Colorectal Cancer
Esophageal Neoplasms

Interacting Proteins

C1orf94
CEP170P1
EIF4ENIF1
GCC1
KRT15

MIS18A
MIS18BP1
NUP62
RAF1
SHISA6

SKIL
TFIP11
TPM3
TRIP6

Pathways

Senescence
Telophase
Cell Death
Cell Cycle
G1 Phase
Mitosis
Interphase

Localization
Anaphase

PTMs

Acetylation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OIP5

References

PMID: 9466265 by Williams J.M., et al. Using the yeast two-hybrid system to identify human epithelial cell proteins that bind gonococcal Opa proteins: intracellular gonococci bind pyruvate kinase via their Opa proteins and require host pyruvate for growth.

PMID: 17199038 by Fujita Y., et al. Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1.