Oligodendrocyte transcription factor 2 (OLIG2)

Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as to the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation.

Cooperates with OLIG1 to set up that the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.