OPCML Antibodies

AND OPCML ELISA kits, OPCML Proteins

Many biological assays use antibodies to detect OPCML, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OPCML in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OPCML antibodies...

We validate the specificity of these antibodies to OPCML by testing them on tissues known to express OPCML positively and negatively. Browse below to find the OPCML antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: OPHN1

OPCML Infographic by Boster Bio

All OPCML Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

OPCML (NM_001012393) Human Recombinant Protein

Coomassie blue staining of purified OPCML protein

$1249
Cat # PROTQ14982
20 µg

OPCML (NM_002545) Human Over-expression Lysate

OPCML Human Over-expression Lysates NM_001012393

Human

$628
Cat # LS004978
20 µg, 100 µg

OPCML Overview

Facts about Opioid-binding protein/cell adhesion molecule.

OPCML 3D structure. Source: alphafold

Opioid-binding protein/cell adhesion molecule (OPCML)

Binds opioids in the presence of acidic lipids; likely involved in cell contact. .

Gene Information

Human
Gene Name:	OPCML
Uniprot:	Q14982
Entrez:	4978

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

IgLON family member 1; IGLON1opioid-binding protein/cell adhesion molecule-like; OBCAM; OBCAMopiate binding-cell adhesion molecule; OPCM; OPCML; opioid binding protein/cell adhesion molecule-like preprotein; opioid binding protein/cell adhesion molecule-like; Opioid-binding cell adhesion molecule; opioid-binding protein/cell adhesion molecule

Molecular Weight

Mass (kDA):
38.008 kDA

Genomic Context


Human

Location:	11q25
Sequence:	11; NC_000011.10 (132403361..133532534, complement)

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

Diseases

Tissue Adhesions
Neoplasms
Malignant Neoplasms
Carcinoma
Ovarian Neoplasm
Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer
Nervousness
Malignant Neoplasm Of Lung
Neoplasm Metastasis
Carcinogenesis
Lung Neoplasms
Neuroblastoma

Lymphatic Metastasis
Glioma
Cell Transformation, Neoplastic
Cholangiocarcinoma
Adenocarcinoma
Neoplasm Recurrence, Local
Liver Carcinoma

Pathways

Cell Adhesion
Methylation
Localization
Dna Methylation
Dna Hypermethylation
Demethylation
Cell Proliferation
Cell-cell Recognition
Gene Silencing
Glycosylation
Dna Hypomethylation
Endocytosis
Ovulation

Axon Guidance
Cellular Localization
Cell Cycle
Hatching
Cell Growth
Pathogenesis
Exocytosis

PTMs

Methylation
Glycosylation

Demethylation
Ribosylation

Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OPCML

References

PMID: 7721093 by Shark K.B., et al. Cloning, sequencing and localization to chromosome 11 of a cDNA encoding a human opioid-binding cell adhesion molecule (OBCAM).

PMID: 12819783 by Sellar G.C., et al. OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.