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- Table of Contents
Facts about Ornithine decarboxylase antizyme 3.
Doesn't target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240). Stabilizes AZIN2 by interfering with its ubiquitination.
| Human | |
|---|---|
| Gene Name: | OAZ3 |
| Uniprot: | Q9UMX2 |
| Entrez: | 51686 |

| Belongs to: |
|---|
| ODC antizyme family |

antizyme 3; AZ3; OAZ-t; ODC-Az 3; ornithine decarboxylase antizyme 3; TISP15
Mass (kDA):
27.413 kDA

| Human | |
|---|---|
| Location: | 1q21.3 |
| Sequence: | 1; NC_000001.11 (151762969..151771330) |
Testis specific.
Nucleus. Cytoplasm.





PMID: 10781085 by Ivanov I.P., et al. Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3.
PMID: 17900240 by Kanerva K., et al. Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase.