Otogelin Antibodies

AND Otog ELISA kits, Otogelin Proteins

Many biological assays use antibodies to detect Otogelin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Otogelin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Otogelin antibodies...

We validate the specificity of these antibodies to Otogelin by testing them on tissues known to express Otog positively and negatively. Browse below to find the Otog antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Otog Infographic by Boster Bio

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OTOGL (NM_173591) Human Over-expression Lysate

Human

$628
Cat # LS283310
20 µg, 100 µg

Otog Overview

Facts about Otogelin.

Otogelin (Otog)

Glycoprotein specific to acellular membranes of the inner ear. Might be required for the anchoring of the otoconial membranes and cupulae into the underlying neuroepithelia from the vestibule.

May be involved in the organization and/or stabilization of the fibrillar system that write the tectorial membrane in the cochlea. May play a role in mechanotransduction processes.

Gene Information

Mouse
Gene Name:	Otog
Uniprot:	O55225
Entrez:	18419

Family

Belongs to:

otogelin family

Alternative Names

Otogelin

Molecular Weight

Mass (kDA):
313.62 kDA

Genomic Context


Mouse

Location:	7 B3\|7 29.66 cM
Sequence:	7;

Tissue Specificity

Expressed specifically in neuroepithelial supporting cells of the inner ear. Expressed in the cochlea between postnatal day P0 and P6 in pseudostratified cells of the greater epithelial ridge, in supporting cells of the neuroepithelium comprising Deiter's, Hensen's, pillar and Claudius cells, in epithelial cells of the Reissner's membrane, in a small set of cells comprising the spiral prominence. Expressed in the cochlea at P15 in interdental cells located underneath the limbal part of the tectorial membrane. Expressed in the vestibular apparatus at P0 in supporting cells of the saccular, utricular maculae and cristae ampullares, in the epithelial cells of the roof of the saccule but not in the roof of the utricle and cristae ampullares (at protein level). Expressed in the cochlea and vestibular organ of the inner ear.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Otog

References

PMID: 9405633 by Cohen-Salmon M., et al. Otogelin: a glycoprotein specific to the acellular membranes of the inner ear.

PMID: 10655058 by Simmler M.C., et al. Targeted disruption of otog results in deafness and severe imbalance.