P2X purinoceptor 3 Antibodies

AND P2RX3 ELISA kits, P2X purinoceptor 3 Proteins

Many biological assays use antibodies to detect P2X purinoceptor 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with P2X purinoceptor 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop P2X purinoceptor 3 antibodies...

We validate the specificity of these antibodies to P2X purinoceptor 3 by testing them on tissues known to express P2RX3 positively and negatively. Browse below to find the P2RX3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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P2RX3 Infographic by Boster Bio

All P2RX3 Products

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Anti-P2X3 P2RX3 Antibody

Immunohistochemistry validation of P2RX3 using Anti-P2X3 P2RX3 Antibody (A05861-2)

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A05861-2
100ul

P2X3 (P2RX3) (NM_002559) Human Over-expression Lysate

Human

$628
Cat # LS005024
20 µg, 100 µg

P2RX3 Overview

Facts about P2X purinoceptor 3.

P2RX3 3D structure. Source: alphafold

P2X purinoceptor 3 (P2RX3)

Receptor for ATP that acts as a ligand-gated cation channel (PubMed:27626375). Plays a role in sensory perception.

Required for normal perception of pain. Required for normal taste perception (By similarity).

Gene Information

Human
Gene Name:	P2RX3
Uniprot:	P56373
Entrez:	5024

Family

Belongs to:

P2X receptor family

Alternative Names

ATP receptor; MGC129956; P2RX3; P2X purinoceptor 3; P2X receptor, subunit 3; P2X3; P2X3purinergic receptor P2X3; purinergic receptor P2X, ligand-gated ion channel, 3; Purinergic receptor; purinoceptor P2X3

Molecular Weight

Mass (kDA):
44.289 kDA

Genomic Context


Human

Location:	11q12.1
Sequence:	11; NC_000011.10 (57335943..57372399)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Pain
Hyperalgesia
Nervousness
Neuralgia
Inflammation
Hyperalgesias, Mechanical
Nerve Damage
Thermal Hyperalgesia
Chronic Pain
Pathological Dilatation
Peripheral Nerve Injuries

Migraine Disorders
Stenosis
Malignant Neoplasms
Peripheral Neuropathy
Cystitis
Visceral Pain

Pathways

Localization
Innervation
Sensitization
Synaptic Transmission
Response To Atp
Hypersensitivity
Reflex
Sensory Processing
Micturition
Transport
Secretion
Aging
Translation

Insulin Secretion
Rna Interference
Cell Adhesion
Gene Silencing
Electron Transport
Electron Transport Chain
Muscle Contraction

PTMs

Phosphorylation
Reduction
Carboxylation

Biotinylation
Phosphorothioation
Dephosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/P2RX3

References

PMID: 9016352 by Garcia-Guzman M., et al. Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.

PMID: 27626375 by Mansoor S.E., et al. X-ray structures define human P2X(3) receptor gating cycle and antagonist action.