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Pannexin-1 Antibodies

AND PANX1 ELISA kits, Pannexin-1 Proteins

Many biological assays use antibodies to detect Pannexin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pannexin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pannexin-1 antibodies...

We validate the specificity of these antibodies to Pannexin-1 by testing them on tissues known to express PANX1 positively and negatively. Browse below to find the PANX1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PANX1 Infographic by Boster Bio

PANX1 protein infographic

All PANX1 Products

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Specificity

Applications

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Anti-Pannexin-1 PANX1 Antibody

Western blot analysis of PANX1 in human ovary tissue lysate with PANX1 antibody at 1 μg/mL

Western blot analysis of PANX1 in human ovary tissue lysate with PANX1 antibody at 1 μg/mL

Immunofluorescence of PANX1 in human ovary tissue with PANX1 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, WB

$481
Cat # A00915
0.1 mg

Anti-Pannexin 1 Rabbit Monoclonal Antibody

Western blot analysis of Pannexin 1 expression in Caco-2 cell lysate

Western blot analysis of Pannexin 1 expression in Caco-2 cell lysate

Human

IP, WB

$370
Cat # M00915
100 μl/vial

Anti-Pannexin 1/PANX1 Antibody Picoband®

1 Citations

Western blot analysis of Pannexin 1/PANX1 using anti-Pannexin 1/PANX1 antibody (A00915-2)

Western blot analysis of Pannexin 1/PANX1 using anti-Pannexin 1/PANX1 antibody (A00915-2)

IF analysis of Pannexin 1/PANX1 using anti-Pannexin 1/PANX1 antibody (A00915-2)

Flow Cytometry analysis of MCF-7 cells using anti-Pannexin 1/PANX1 antibody (A00915-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A00915-2
100 μg/vial

PANX1 Overview

Facts about Pannexin-1.

PANX1 3D structure

PANX1 3D structure. Source: alphafold

Pannexin-1 (PANX1)

Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to modulate ER Ca(2+) homeostasis.

.

Gene Information

Human
Gene Name:	PANX1
Uniprot:	Q96RD7
Entrez:	24145

Gene Information

Family

Belongs to:

pannexin family

Family

Alternative Names

Innexin; MGC21309; MRS1; MRS1innexin; pannexin 1; Pannexin1; Pannexin-1; PANX1; PX1; UNQ2529

Molecular Weight

Mass (kDA):
48.05 kDA

Molecular Weight

Genomic Context


Human

Location:	11q21
Sequence:	11; NC_000011.10 (94128841..94185596)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Nervousness
Inflammation
Ischemia
Neoplasms
Epilepsy
Neuroblastoma
Edema
Malignant Neoplasms
Cerebrovascular Accident
Nerve Degeneration
Glioma
Physiological Stress

Neurodegenerative Disorders
Melanoma
Hypoxia
Malignant Paraganglionic Neoplasm
Reperfusion Injury
Infarction
Anoxia

Disease

Pathways

Localization
Cell Death
Secretion
Transport
Glycosylation
Cell Proliferation
Cell Communication
Cellular Localization
Cell Activation
Immune Response
Keratinocyte Differentiation
Membrane Depolarization
Paracrine Signaling

Neuroprotection
T Cell Anergy
Apoptotic Cell Clearance
Cell Adhesion
Signal Release
Cell Migration
Gene Silencing

Pathways

PTMs

Glycosylation
Phosphorylation
Cleavage
Biotinylation

Deglycosylation
Nitrosylation
Formylation
Dephosphorylation

Palmitoylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PANX1

References

PMID: 15028292 by Baranova A., et al. The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins.

PMID: 16908669 by Vanden Abeele F., et al. Functional implications of calcium permeability of the channel formed by pannexin 1.