PBX2 Antibodies

AND PBX2 ELISA kits, PBX2 Proteins

Many biological assays use antibodies to detect PBX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PBX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PBX2 antibodies...

We validate the specificity of these antibodies to PBX2 by testing them on tissues known to express PBX2 positively and negatively. Browse below to find the PBX2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PBX2 Infographic by Boster Bio

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PBX2 (NM_002586) Human Over-expression Lysate

Human

$628
Cat # LS005089
20 µg, 100 µg

PBX2 Overview

Facts about Pre-B-cell leukemia transcription factor 2.

PBX2 3D structure. Source: alphafold

Pre-B-cell leukemia transcription factor 2 (PBX2)

Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1.

Gene Information

Human
Gene Name:	PBX2
Uniprot:	P40425
Entrez:	5089

Family

Belongs to:

TALE/PBX homeobox family

Alternative Names

G17Homeobox protein PBX2; HOX12homeobox 12; PBX2MHC; pre-B-cell leukemia homeobox 2; pre-B-cell leukemia transcription factor 2; Protein G17

Molecular Weight

Mass (kDA):
45.881 kDA

Genomic Context


Human

Location:	6p21.32
Sequence:	6; NC_000006.12 (32184733..32190202, complement)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Chromosomal Translocation
Precursor B-cell Lymphoblastic Leukemia-lymphoma
Carcinoma
Myeloid Leukemia
Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasms
Leukemogenesis
Embryonal Carcinoma
Leukemia, Myelocytic, Acute
Malignant Squamous Cell Neoplasm
Dementia

Tumor Angiogenesis
Lymphoma
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Leukemia, B-cell
Malignant Neoplasm Of Lung
Neoplasm Metastasis

Interacting Proteins

CARD9
HOXA1

Pathways

Pathogenesis
Cell Differentiation
Localization
Limb Development
Segmentation
Muscle Cell Differentiation
Reverse Transcription
Translation
Hindbrain Development
Angiogenesis
Neural Crest Cell Differentiation
Skin Development
Cell Fate Determination

Neurogenesis
Ossification
Virulence
Cell Division
Mrna Processing
Eye Development
Contact Inhibition

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PBX2

References

PMID: 1682799 by Monica K., et al. PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.

PMID: 7759099 by Aguado B., et al. The novel gene G17, located in the human major histocompatibility complex, encodes PBX2, a homeodomain-containing protein.