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- Table of Contents
PDCD10 Antibodies
AND PDCD10 ELISA kits, PDCD10 Proteins
Many biological assays use antibodies to detect PDCD10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDCD10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDCD10 antibodies...
Designing a Western blot for PDCD10? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PDCD10 Western Blot GuidePDCD10 Infographic by Boster Bio
All PDCD10 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01880-1
100 µg/vial
Cat # A01880-1
100 µg/vial
PDCD10 Overview
Facts about Programmed cell death protein 10.
Programmed cell death protein 10 (PDCD10)
Promotes cell proliferation. Modulates apoptotic pathways.
Increases mitogen-activated protein kinase activity and STK26 activity (PubMed:27807006). Important for cell migration, and for regular structure and assembly of the Golgi complex (PubMed:27807006).
Gene Information
| Human | |
|---|---|
| Gene Name: | PDCD10 |
| Uniprot: | Q9BUL8 |
| Entrez: | 11235 |
Family
| Belongs to: |
|---|
| PDCD10 family |
Alternative Names
apoptosis-related protein 15; cerebral cavernous malformations 3; MGC1212; MGC24477; programmed cell death 10; programmed cell death protein 10; TF-1 cell apoptosis-related protein 15; TFAR15CCM3Cerebral cavernous malformations 3 protein
Molecular Weight
Mass (kDA):
24.702 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q26.1 |
| Sequence: | 3; NC_000003.12 (167683298..167735810, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Partially co-localizes with endogenous PXN at the leading edges of migrating cells.
Diseases
- Cavernous Hemangioma Of Brain
- Hemangioma, Cavernous, Central Nervous System
- Cerebrovascular Accident
- Nervousness
- Vascular Anomaly
- Headache
- Hemorrhage
- Brain Hemorrhage
- Brain Neoplasms
- Congenital Vascular Anomaly
- Tumor Angiogenesis
- Malignant Neoplasms
Interacting Proteins
- C4orf19
- CCM2
- PTPN13
- STK24
- STK25
- STK26
- STRN
Pathways
- Cell Death
- Pathogenesis
- Programmed Cell Death
- Angiogenesis
- Cell Proliferation
- Localization
- Tube Formation
- Vasculogenesis
- Cell Cycle
- Cell Migration
- Hyperphosphorylation
- Golgi Localization
- Gene Silencing
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDCD10
bosterbio.com/bosterbio-gene-info-cards/PDCD10
References
PMID: 15543491 by Bergametti F., et al. Mutations within the programmed cell death 10 gene cause cerebral cavernous malformations.
PMID: 17360971 by Ma X., et al. PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway.