PDE6H Antibodies

AND PDE6H ELISA kits, PDE6H Proteins

Many biological assays use antibodies to detect PDE6H, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDE6H in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDE6H antibodies...

We validate the specificity of these antibodies to PDE6H by testing them on tissues known to express PDE6H positively and negatively. Browse below to find the PDE6H antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDE6H Infographic by Boster Bio

All PDE6H Products

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PDE6H (NM_006205) Human Recombinant Protein

Coomassie blue staining of purified PDE6H protein

$1249
Cat # PROTQ13956
20 µg

PDE6H (NM_006205) Human Over-expression Lysate

Human

$628
Cat # LS005149
20 µg, 100 µg

PDE6H Overview

Facts about Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.

PDE6H 3D structure. Source: alphafold

Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (PDE6H)

Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

Gene Information

Human
Gene Name:	PDE6H
Uniprot:	Q13956
Entrez:	5149

Family

Belongs to:

rod/cone cGMP-PDE gamma subunit family

Alternative Names

Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

Molecular Weight

Mass (kDA):
9.074 kDA

Genomic Context


Human

Location:	12p12.3
Sequence:	12; NC_000012.12 (14973042..14981865)

Diseases

Cone dystrophy, retinal 3A (RCD3A)

Interacting Proteins

COTL1

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDE6H

References

PMID: 8786098 by Shimizu-Matsumoto A., et al. Isolation and chromosomal localization of the human cone cGMP phosphodiesterase gamma cDNA (PDE6H).

PMID: 15629837 by Piri N., et al. A substitution of G to C in the cone cGMP-phosphodiesterase gamma subunit gene found in a distinctive form of cone dystrophy.