PFKFB4 Antibodies

AND PFKFB4 ELISA kits, PFKFB4 Proteins

Many biological assays use antibodies to detect PFKFB4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PFKFB4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PFKFB4 antibodies...

We validate the specificity of these antibodies to PFKFB4 by testing them on tissues known to express PFKFB4 positively and negatively. Browse below to find the PFKFB4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PFKFB4 Infographic by Boster Bio

All PFKFB4 Products

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Product

Figures

Specificity

Applications

Price

Anti-PFKFB4 Mouse Monoclonal Antibody [Clone ID: OTI1C8]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PFKFB4 (Right lane) cDNA for 48 hrs and lysed

Anti-PFKFB4 mouse monoclonal antibody (M07028) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PFKFB4

Immunofluorescent staining of HepG2 cells using anti-PFKFB4 mouse monoclonal antibody (M07028)

Human, Mouse, Rat

IF, WB

$523
Cat # M07028
100 µl

PFKFB4 (NM_004567) Human Over-expression Lysate

Human

$628
Cat # LS005210
20 µg, 100 µg

Anti-PFKFB4 Antibody Picoband®

Western blot analysis of PFKFB4 using anti-PFKFB4 antibody (A07028-1)

Human

ELISA, WB

$370
Cat # A07028-1
100 µg/vial

PFKFB4 Overview

Facts about 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4.

PFKFB4 3D structure. Source: alphafold

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4)

Synthesis and degradation of fructose 2,6-bisphosphate. .

Gene Information

Human
Gene Name:	PFKFB4
Uniprot:	Q16877
Entrez:	5210

Family

Belongs to:

No superfamily

Alternative Names

6PF-2-K/Fru-2,6-P2ase 4; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4,6PF-2-K/Fru-2,6-P2ase 4,6PF-2-K/Fru-2,6-P2ase testis-type isozyme; bifunctional enzyme with kinase and biphosphatase activities; PFK/FBPase 4; PFKFB4

Molecular Weight

Mass (kDA):
54.04 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (48517684..48562383, complement)

Diseases

Malignant Neoplasms
Hypoxia
Neoplasms
Liver Carcinoma
Malignant Paraganglionic Neoplasm
Carcinoma
Malignant Neoplasm Of Prostate
Pancreatic Neoplasm
Mammary Neoplasms
Cadmium Poisoning
Prediabetes Syndrome
Stomach Neoplasms

Melanoma
Tumor Progression
Colonic Neoplasms
Malignant Tumor Of Colon
Glioma
Malignant Neoplasm Of Liver
Malignant Neoplasm Of Urinary Bladder

Pathways

Glycolysis
Cell Proliferation
Localization
Cell Death
Cell Cycle
Cell Activation
Gene Silencing
T Cell Aggregation
T Cell Activation
Response To Hypoxia
Hypersensitivity
Gluconeogenesis
Regulation Of Glycolysis

Spermatogenesis
Cell Cycle Arrest
Glucose Homeostasis
Translation
Cellular Localization
T Cell Proliferation
Angiogenesis

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PFKFB4

References

PMID: 15474002 by Minchenko O., et al. Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose- 2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation.

PMID: 10095107 by Manzano A., et al. Cloning, expression and chromosomal localization of a human testis 6- phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene.