PGAP2 Antibodies

AND PGAP2 ELISA kits, PGAP2 Proteins

Many biological assays use antibodies to detect PGAP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PGAP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PGAP2 antibodies...

We validate the specificity of these antibodies to PGAP2 by testing them on tissues known to express PGAP2 positively and negatively. Browse below to find the PGAP2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PGAP2 Infographic by Boster Bio

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PGAP2 (NM_014489) Human Over-expression Lysate

PGAP2 Human Over-expression Lysates NM_001145439

Human

$628
Cat # LS027315
20 µg, 100 µg

PGAP2 Overview

Facts about Post-GPI attachment to proteins factor 2.

PGAP2 3D structure. Source: alphafold

Post-GPI attachment to proteins factor 2 (PGAP2)

Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins in the cell surface (By similarity).

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Gene Information

Human
Gene Name:	PGAP2
Uniprot:	Q9UHJ9
Entrez:	27315

Family

Belongs to:

PGAP2 family

Alternative Names

Post-GPI attachment to proteins factor 2

Molecular Weight

Mass (kDA):
29.4 kDA

Genomic Context


Human

Location:	11p15.4
Sequence:	11; NC_000011.10 (3797724..3826371)

Tissue Specificity

Ubiquitously expressed, with highest levels in testis and pancreas.

Subcellular Localizations

Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Hyperphosphatasia with mental retardation syndrome 3 (HPMRS3)

Interacting Proteins

CREB3L1
KRTAP10-9

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGAP2

References

PMID: 10585768 by Lorenzi M.V., et al. Human FRAG1 encodes a novel membrane-spanning protein that localizes to chromosome 11p15.5, a region of frequent loss of heterozygosity in cancer.

PMID: 23561846 by Hansen L., et al. Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability.