6-phosphogluconolactonase Antibodies

AND PGLS ELISA kits, 6-phosphogluconolactonase Proteins

Many biological assays use antibodies to detect 6-phosphogluconolactonase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with 6-phosphogluconolactonase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop 6-phosphogluconolactonase antibodies...

We validate the specificity of these antibodies to 6-phosphogluconolactonase by testing them on tissues known to express PGLS positively and negatively. Browse below to find the PGLS antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PGLS Infographic by Boster Bio

All PGLS Products

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Applications

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Anti-6-phosphogluconolactonase PGLS Antibody

Western blot (WB) analysis of PGLS (A226) pAb at 1:500 dilution
Lane1:HCT116 whole cell lysate(40ug)
Lane2:Panc1 whole cell lysate(40ug)
Lane3:HEK293T whole cell lysate(40ug)

Human

IHC, WB

$405
Cat # A02553
100ul

PGLS (NM_012088) Human Recombinant Protein

Coomassie blue staining of purified PGLS protein

$1249
Cat # PROTO95336
20 µg

PGLS (NM_012088) Human Over-expression Lysate

Human

$628
Cat # LS025796
20 µg, 100 µg

Anti-PGLS Antibody Picoband®

Western blot analysis of PGLS using anti-PGLS antibody (A02553-2)

IF analysis of PGLS using anti-PGLS antibody (A02553-2) and anti-Beta Tubulin antibody (M01857-3)

Flow Cytometry analysis of JK cells using anti-PGLS antibody (A02553-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02553-2
100 µg/vial

PGLS Overview

Facts about 6-phosphogluconolactonase.

PGLS 3D structure. Source: alphafold

6-phosphogluconolactonase (PGLS)

Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. .

Gene Information

Human
Gene Name:	PGLS
Uniprot:	O95336
Entrez:	25796

Family

Belongs to:

glucosamine/galactosamine-6-phosphate isomerase family

Alternative Names

6PGLEC 3.1.1.31; 6-phosphogluconolactonase

Molecular Weight

Mass (kDA):
27.547 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (17511649..17521291)

Subcellular Localizations

Cytoplasm.

Diseases

Punctate Inner Choroidopathy
Hypotension Adverse Event
Endocrine Gland Neoplasms
Stenosis
Malignant Neoplasm Of Breast
Von Hippel-lindau Syndrome
Exanthema
Malignant Neoplasms
Neoplasms
Nervousness
Asthma
Mammary Neoplasms

Pheochromocytoma
Paraganglioma
Pathologic Vasoconstriction
Anaphylaxis
Neuroblastoma
Germline Mutation Abnormality
Nerve Degeneration

Interacting Proteins

TERF2IP

Pathways

Tooth Eruption
Anaphylaxis
Pathogenesis
Localization
Platelet Aggregation
Secretion

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGLS

References

PMID: 10518023 by Collard F., et al. Identification of the cDNA encoding human 6-phosphogluconolactonase, the enzyme catalyzing the second step of the pentose phosphate pathway.