PKD2L2 Antibodies

AND PKD2L2 ELISA kits, PKD2L2 Proteins

Many biological assays use antibodies to detect PKD2L2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PKD2L2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PKD2L2 antibodies...

We validate the specificity of these antibodies to PKD2L2 by testing them on tissues known to express PKD2L2 positively and negatively. Browse below to find the PKD2L2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PKD2L2 Infographic by Boster Bio

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PKD2L2 Overview

Facts about Polycystic kidney disease 2-like 2 protein.

PKD2L2 3D structure. Source: alphafold

Polycystic kidney disease 2-like 2 protein (PKD2L2)

May function as a subunit of a cation channel and play a role in fertilization. .

Gene Information

Human
Gene Name:	PKD2L2
Uniprot:	Q9NZM6
Entrez:	27039

Family

Belongs to:

polycystin family

Alternative Names

polycystic kidney disease 2-like 2 protein; polycystic kidney disease 2-like 2; polycystin-L2

Molecular Weight

Mass (kDA):
73.79 kDA

Genomic Context


Human

Location:	5q31.2
Sequence:	5; NC_000005.10 (137889411..137942747)

Tissue Specificity

According to PubMed:10602361, expressed only in testis. According to PubMed:10756092, expressed also in brain and kidney. Isoform 2 is found only in transformed lymphoblasts. Isoform 3 is found in all tissues tested.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Polycystic Kidney Diseases
Kidney Diseases
Polycystic Kidney, Autosomal Dominant
Hereditary Diseases
Mucolipidoses
Kidney Failure

Pathways

Reverse Transcription
Acrosome Reaction
Fertilization
Oocyte Growth
Mating
Mating Behavior
Localization

Spermatogenesis

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PKD2L2

References

PMID: 10602361 by Veldhuisen B., et al. Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2).

PMID: 10756092 by Guo L., et al. Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localization.