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- Table of Contents
Pyruvate kinase PKLR Antibodies
AND PKLR ELISA kits, Pyruvate kinase PKLR Proteins
Many biological assays use antibodies to detect Pyruvate kinase PKLR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pyruvate kinase PKLR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pyruvate kinase PKLR antibodies...
Designing a Western blot for Pyruvate kinase PKLR? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PKLR Western Blot GuideDesigning an IHC experiment for Pyruvate kinase PKLR? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PKLR IHC GuidePKLR Infographic by Boster Bio
All PKLR Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS005313
20 µg, 100 µg
Cat # LS005313
20 µg, 100 µg
PKLR Overview
Facts about Pyruvate kinase PKLR.
Pyruvate kinase PKLR (PKLR)
Plays a crucial role in glycolysis. .
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PKLR |
| Uniprot: | P30613 |
| Entrez: | 5313 |
Family
| Belongs to: |
|---|
| pyruvate kinase family |
Alternative Names
EC 2.7.1.40; PK1; PK1PKRL; PKL; PKLR; PKR; Pyruvate Kinase 1; pyruvate kinase isozyme R/L; pyruvate kinase isozymes R/L; pyruvate kinase type L; pyruvate kinase, liver and blood cell; pyruvate kinase, liver and RBC; Red cell/liver pyruvate kinase; RPK; R-type/L-type pyruvate kinase
Molecular Weight
Mass (kDA):
61.83 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q22 |
| Sequence: | 1; NC_000001.11 (155289293..155301438, complement) |
Diseases
- Pyruvate Kinase Deficiency
- Anemia
- Anemia, Hemolytic
- Malaria
- Anemia, Hemolytic, Congenital Nonspherocytic
- Dysequilibrium Syndrome
- Gaucher Disease
- Diabetes Mellitus
- Parasitemia
- Diabetes Mellitus, Non-insulin-dependent
- Inborn Errors Of Metabolism
- Anemia, Hemolytic, Congenital
Pathways
- Secretion
- Insulin Secretion
- Localization
- Glycolysis
- Transport
- Regulation Of Macroautophagy
- Cell Proliferation
- Cellular Homeostasis
- Dna Methylation
- Regulation Of Gene Expression
- Oxidative Phosphorylation
- Methylation
- Disease Resistance
PTMs
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PKLR
bosterbio.com/bosterbio-gene-info-cards/PKLR
References
PMID: 1896471 by Kanno H., et al. cDNA cloning of human R-type pyruvate kinase and identification of a single amino acid substitution (Thr384-->Met) affecting enzymatic stability in a pyruvate kinase variant (PK Tokyo) associated with hereditary hemolytic anemia.
PMID: 3126495 by Tani K., et al. Human liver type pyruvate kinase: complete amino acid sequence and the expression in mammalian cells.
1 Publications of Boster Pyruvate kinase PKLR Antibodies & ELISA Kits
- PubMed ID: 10.1111/jcmm.13805, miR‐1322 regulates ChREBP expression via binding a 3′‐UTR variant (rs10519...
*More publications can be found for each product on its corresponding product page