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- Table of Contents
Facts about Calcium-dependent phospholipase A2.
May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle. .
| Human | |
|---|---|
| Gene Name: | PLA2G5 |
| Uniprot: | P39877 |
| Entrez: | 5322 |

| Belongs to: |
|---|
| phospholipase A2 family |

Ca2+-dependent phospholipase A2; calcium-dependent phospholipase A2; DKFZp686C2294; EC 3.1.1.4; Group V phospholipase A2; GV-PLA2; hVPLA(2); MGC46205; Phosphatidylcholine 2-acylhydrolase 5; phospholipase A2, group V; PLA2-10
Mass (kDA):
15.674 kDA

| Human | |
|---|---|
| Location: | 1p36.13 |
| Sequence: | 1; NC_000001.11 (20028349..20091911) |
Heart, placenta and less abundantly, in lung. Detected in the outer and inner plexiform layers of the retina (at protein level).
Secreted.





PMID: 8300559 by Chen J., et al. Cloning and recombinant expression of a novel human low molecular weight Ca(2+)-dependent phospholipase A2.
PMID: 22137173 by Sergouniotis P.I., et al. Biallelic mutations in PLA2G5, encoding group V phospholipase A2, cause benign fleck retina.