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- Table of Contents
Facts about Secretory phospholipase A2 receptor.
Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both negative and positive regulation of sPLA2 functions in addition to clearance of sPLA2.
| Mouse | |
|---|---|
| Gene Name: | Pla2r1 |
| Uniprot: | Q62028 |
| Entrez: | 18779 |

| Belongs to: |
|---|
| No superfamily |

180 kDa secretory phospholipase A2 receptor; CLEC13C; CLEC13CC-type lectin domain family 13 member C; phospholipase A2 receptor 1, 180kDa; PLA2G1R; PLA2IR; PLA2R1; PLA2-RM-type receptor; PLA2Rphospholipase A2 receptor 1, 180kD; secretory phospholipase A2 receptor
Mass (kDA):
170.512 kDA

| Mouse | |
|---|---|
| Location: | 2|2 C1.1-C1.2 |
| Sequence: | 2; |
Widely expressed. Present in type II alveolar epithelial cells and a subset of splenic lymphocytes. Present at the surface of polymorphonuclear neutrophils (at protein level).



PMID: 7925459 by Higashino K., et al. Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals.
PMID: 9407054 by Hanasaki K., et al. Resistance to endotoxic shock in phospholipase A2 receptor-deficient mice.